190381-50-1 Usage
Uses
Used in Pharmaceutical Research:
Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2,6-dimethyl(9CI) is utilized as a building block in the synthesis of pharmaceutical compounds for its unique structural features and potential to contribute to the development of new drugs.
Used in Medicinal Chemistry:
Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2,6-dimethyl(9CI) serves as a subject of interest in medicinal chemistry due to its potential biological activities and effects, which could be harnessed in the design and discovery of novel therapeutic agents.
Used in Drug Discovery:
Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2,6-dimethyl(9CI) is employed in drug discovery processes to explore its potential as a lead compound or as a component in the creation of new pharmaceutical entities with therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 190381-50-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,3,8 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 190381-50:
(8*1)+(7*9)+(6*0)+(5*3)+(4*8)+(3*1)+(2*5)+(1*0)=131
131 % 10 = 1
So 190381-50-1 is a valid CAS Registry Number.
190381-50-1Relevant academic research and scientific papers
Research on heterocyclic compounds. XXXVII. Synthesis and antiinflammatory activity of methyl-substituted imidazo[1,2-a]pyrazine derivatives
Rimoli,Avallone,De Caprariis,Luraschi,Abignente,Filippelli,Berrino,Rossi
, p. 195 - 203 (2007/10/03)
A series of methyl-substituted imidazo[1,2-a]pyrazines 8 bearing a carboxylic acid group on the imidazole ring were synthesized. The structures of new compounds were confirmed by 1H- and 13C-NMR spectral data; the correct assignment of carbon resonances was made by means of HETCOR and COLOC experiments. Antiinflammatory, analgesic and ulcerogenic activities in vivo were evaluated and compared with those of antiinflammatory imidazopyrazines (2 and 3) and indomethacin. The inhibitory action on cyclooxygenase activity was evaluated in vitro. Compounds 8 were found to be less potent than indomethacin in these assays. SARs are discussed.
