Cas 190388-19-3,Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester

190388-19-3

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Basic information

Product Name: Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester
Synonyms: Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester
CAS NO:190388-19-3
Molecular Formula:
Molecular Weight: 529.557
EINECS: N/A
Product Categories: N/A
Mol File: 190388-19-3.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester(190388-19-3)
EPA Substance Registry System: Acetic acid 4-{(S)-2-methyl-1-[(S)-2-(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-pyrrolidine-1-carbonyl]-propylcarbamoyl}-phenyl ester(190388-19-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 190388-19-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 190388-19-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,3,8 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 190388-19:
(8*1)+(7*9)+(6*0)+(5*3)+(4*8)+(3*8)+(2*1)+(1*9)=153
153 % 10 = 3
So 190388-19-3 is a valid CAS Registry Number.

190388-19-3Upstream product

2345-34-8 4-acetyloxy-benzoic acid

190388-19-3Downstream Products

190387-57-6 (3RS)-(4-acetoxybenzoyl)-L-valyl-N-[3-(1,1,1-trifluoro-4-methyl-2-oxopentyl)]-L-prolinamide

190388-19-3Relevant articles and documents

Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase

Edwards, Philip D.,Andisik, Donald W.,Bryant, Craig A.,Ewing, Barbara,Gomes, Bruce,Lewis, Joseph J.,Rakiewicz, Donna,Steelman, Gary,Strimpler, Ann,Trainor, Diane A.,Tuthill, Paul A.,Mauger, Russell C.,Veale, Chris A.,Wildonger, Richard A.,Williams, Joseph C.,Wolanin, Donald J.,Zottola, Mark

, p. 1876 - 1885 (2007/10/03)

Previously we had shown that tripeptidyl trifluoromethyl ketones (TFMKs) possessing an N-terminal diarylacylsulfonamide, such as ICI 200,880 and ICI 200,355, displayed unparalleled protection against the lung damage induced by human neutrophil elastase (H

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