190435-25-7Relevant academic research and scientific papers
One step preparation and 1,3-dipolar cycloadditions of (S)-5-hydroxymethyl-1-pyrroline N-oxide
Closa, Montserrat,De March, Pedro,Figueredo, Marta,Font, Josep
, p. 1031 - 1037 (1997)
The cyclic nitrone 1b has been prepared in enantiomerically pure form by direct oxidation of L-(+)-prolinol with dimethyldioxirane. A complete diastereoface differentiation has been observed in the 1,3-dipolar cycloaddition reaction of this nitrone to several 1,2-disubstituted electron deficient olefins.
