190448-86-3

Upstream product

• 110-62-3 pentanal 
• 190448-84-1 (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide 
• 10439-23-3 4-methylbenzenesulfinyl chloride 

Downstream Products

• 131154-14-8 4-Methyl-benzenesulfinic acid ((R)-1-phenyl-pentyl)-amide 
• 131154-13-7 4-Methyl-benzenesulfinic acid ((S)-1-phenyl-pentyl)-amide 
• 20675-59-6 (S)-1-methyl-4-(phenylsulfinyl)benzene 
• 852332-94-6 [1R,2S,(S)S]-N-{1-butyl-2-[(S)-2-(p-toluenesulfinyl)phenyl]-2-(methylthio)ethyl}-p-toluenesulfinamide 
• 909409-98-9 [1R,2S,SS]-N-[1-butyl-2-phenyl-2-(methylthio)ethyl]-p-toluene sulfinamide 

Relevant academic research and scientific papers

Asymmetric synthesis of chiral sulfoxides and sulfinimines by using N-sulfinylsultam

Bornane-10,2-sultam 1 is stereoselectively converted by DMAP-assisted sulfinylation to diastereomerically pure (2R)-N-[(R)-p-tolylsulfinyl]-bornane-10,2-sultam 2 in 77% yield. The crystalline sulfinylating agent 2 reacts with a variety of nucleophiles to afford sulfoxides 3 and sulfinimines 5 in excellent yields and enantioselectivities.