190448-84-1

Basic information

• Product Name: (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide
• Synonyms: (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide
• CAS NO: 190448-84-1
• Molecular Weight: 353.507
• Mol File: 190448-84-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide(190448-84-1)
• EPA Substance Registry System: (1S,5R,7R)-10,10-Dimethyl-4-((R)-toluene-4-sulfinyl)-3-thia-4-aza-tricyclo[5.2.1.0^1,5]decane 3,3-dioxide(190448-84-1)

Safety Data

• Hazardous Substances Data: 190448-84-1(Hazardous Substances Data)

Upstream product

• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 94594-90-8 (2R)-bornane-10,2-sultam 

Downstream Products

• 186249-72-9 (+)-(S)-(E)-N-(3-E-phenylpropenylidene)-p-toluenesulfinamide 
• 188447-82-7 (S)-(+)-N-(crotonylidene)-p-toluenesulfinamide 
• 190448-86-3 4-Methyl-benzenesulfinic acid (S)-pent-(E)-ylideneamide 
• 58059-08-8 tert-butyl (R)-p-toluenesulfinylacetate 
• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 54828-68-1 (R)-p-tolyl vinyl sulfoxide 
• 30506-35-5 (R)-1-(butylsulfinyl)-4-methylbenzene 
• 156767-62-3 (R,E)-1-methyl-4-(prop-1-en-1-ylsulfinyl)benzene 
• 89708-79-2 (R)-(+)-allyl p-tolyl sulphoxide 
• 1517-74-4 (+)-(R)-isopropyl p-tolyl sulfoxide 
• 99930-80-0 1-pentynyl p-tolyl (+)-(S)-sulfoxide 
• 4820-08-0 (R)-1-(benzylsulfinyl)-4-methylbenzene 
• 143810-77-9 (S_S)-2-(p-tolylsulfinyl)thiophene 
• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 

Relevant articles and documents

Asymmetric synthesis of chiral sulfoxides and sulfinimines by using N-sulfinylsultam

Bornane-10,2-sultam 1 is stereoselectively converted by DMAP-assisted sulfinylation to diastereomerically pure (2R)-N-[(R)-p-tolylsulfinyl]-bornane-10,2-sultam 2 in 77% yield. The crystalline sulfinylating agent 2 reacts with a variety of nucleophiles to afford sulfoxides 3 and sulfinimines 5 in excellent yields and enantioselectivities.