19051-10-6Relevant academic research and scientific papers
THE ISOMERIZATION/CHLORINATION OF O,O-DIALKYL PHENYLTHIOPHOSPHONATES WITH PHOSPHORUS OXYCHLORIDE - A NEW CONVENIENT SYNTHESIS OF S-ALKYL PHENYLTHIOPHOSPHONIC ACID DERIVATIVES
Tang, Chu Chi,Wu, Gui Ping,Huang, Guang Yan,Li, Zhen,Jin, Gui Yu
, p. 159 - 164 (2007/10/02)
A new method for the synthesis of S-alkyl phenylthiophosphonic acid derivatives is reported.The chlorination of O,O-dialkyl phenylthiophosphonates with phosphorus oxychloride proceeds with isomerization to give S-alkyl phenylthiophosphonochloridates, which react further with various nucleophiles in the presence of triethylamine to give the title compounds.Key words: Phosphonothionate; phosphonothiolate; phosphonodithiolate; phosphonamidethiolate; isomerization; chlorination.
