19063-16-2 Usage
Uses
Used in Polymer and Plastics Industry:
(4-chlorophenyl)sulfamic acid is used as a flame retardant for enhancing the fire safety of polymers and plastics. Its incorporation into these materials helps to slow down or prevent the spread of flames, thereby improving the safety standards of the final products.
Used in Cleaning Agents Production:
In the cleaning agents industry, (4-chlorophenyl)sulfamic acid serves as an additive that enhances the effectiveness of cleaning products. Its inclusion can boost the cleaning power and potentially extend the range of stains and dirt that the products can remove.
Used in Corrosion Inhibitors Production:
(4-chlorophenyl)sulfamic acid is utilized as a component in corrosion inhibitors, which are essential in protecting metals from the damaging effects of corrosion. Its presence in these inhibitors contributes to the longevity and durability of metal structures and machinery.
Used in Pharmaceutical Synthesis:
(4-chlorophenyl)sulfamic acid is employed as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical properties make it a valuable building block in the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Synthesis:
Similarly, in the agrochemical sector, (4-chlorophenyl)sulfamic acid is used in the synthesis of compounds that protect crops from pests and diseases, thereby contributing to increased agricultural productivity and food security.
Used in Disease Treatment Research:
(4-chlorophenyl)sulfamic acid is also being studied for its potential therapeutic applications in treating diseases such as cancer and diabetes. Its inhibitory effects on certain enzymes suggest that it may play a role in managing or treating these conditions, although further research is necessary to confirm its efficacy and safety in a clinical setting.
Check Digit Verification of cas no
The CAS Registry Mumber 19063-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,6 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19063-16:
(7*1)+(6*9)+(5*0)+(4*6)+(3*3)+(2*1)+(1*6)=102
102 % 10 = 2
So 19063-16-2 is a valid CAS Registry Number.
19063-16-2Relevant academic research and scientific papers
Synthesis of sulfamide analogues of deoxthymidine monophosphate as potential inhibitors of mycobacterial cell wall biosynthesis
Suthagar, Kajitha,Jiao, Wanting,Munier-Lehmann, Hélène,Fairbanks, Antony J.
, p. 32 - 40 (2018/01/26)
The recently discovered enzyme Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt), which catalyses the phosphorylation of deoxythymidine monophosphate (dTMP) to give deoxythymidine diphosphate (dTDP), is indispensable for the growth and survival of M. tuberculosis as it plays an essential role in DNA synthesis. Inhibition of TMPKmt is an attractive avenue for the development of novel anti-tuberculosis agents. Based on the premise that sulfamide may be a suitable isostere of phosphate, deoxythymidine analogues comprising various substituted sulfamides at C5′ were modelled in silico into the active site of TMPKmt (PDB accession code: 1N5K) using induced-fit docking methods. A selection of modelled compounds was synthesized, and their activity as inhibitors of TMPKmt was evaluated. Three compounds showed competitive inhibition of TMPKmt in the micromolar range (10–50 μM). Compounds were tested in vitro for anti-mycobacterial activity against M. smegmatis: three compounds showed weak anti-mycobacterial activity (MIC 250 μg/mL).
