19063-71-9

Usage

Also known as

3,3-bis(methylthio)-1-phenyl-1-propanone

Type of compound

keto-thioether

Odor

Distinctive

Common uses

Organic synthesis, reagent in the synthesis of pharmaceuticals and agrochemicals, production of fragrances and flavors

Functional group

Sulfur-containing, which imparts a unique aroma

Antimicrobial and antifungal properties

Useful in various industrial and medical applications

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 62762-49-6 tributylstannane 
• 13636-88-9 3,3-bis(methylthio)-1-phenylprop-2-en-1-one 
• 29866-41-9 2-(bis(methylthio)methylene)-1-phenylbutane-1,3-dione 

Downstream Products

• 4325-77-3 2-phenylphenanthrene 
• 74291-91-1 α-<2,2-bis(methylthio)ethyl>benzenemethanol 
• 612-94-2 2-phenylnaphthalene 
• 156944-22-8 3,3-Bis-methylsulfanyl-1-phenyl-butan-1-ol 
• 156944-25-1 3,3-bis(methylthio)-1-phenyl-1-propene 
• 1196-67-4 (E)-β-methylcinnamaldehyde 
• 1210-39-5 3,3-diphenyl-2-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 4492-01-7 1,3-diphenyl-1H-pyrazole 

Relevant academic research and scientific papers

Highly regioselective 1,2-addition of alkoxybenzyl Grignard reagents to α-oxoketene dithioacetals: A facile regiocontrolled synthesis of alkoxynaphthalenes and their condensed analogs via aromatic annelation

4-Methoxybenzyl- (A), 3,4-dimethoxybenzyl- (B) and 3,4- methylenedioxybenzyl- (C) Grignard reagents are shown to undergo regioselective 1,2-addition with various acyclic and cyclic α-oxoketene dithioacetals to afford carbinol dithioacetals which on BFsub

Unexpected hydrobromic acid-catalyzed C-C bond-forming reactions and facile synthesis of coumarins and benzofurans based on ketene dithioacetals

Hydrobromic acid was found to be a unique catalyst in C-C bond-forming reactions with ketene dithioacetals. Distinctly different from other acids (including Lewis and Bronsted acids), the remarkable catalytic performance of hydrobromic acid in catalytic a

Chemoselective conjugate 1,4-reduction of α-oxoketene dithioacetals with zinc in acetic acid: Synthesis of β-oxodithioacetals

Acyl ketene dithioacetals 1 and 3 undergo highly chemoselective conjugate 1,4-reduction with zinc in acetic acid to give β-oxodithioacetals 2 and 4 in high yields.

Oxidative Generation of Thioalkyl Cations from 2-Tributylstannyl-1,3-dithianes and 1-(Tributylstannyl)alkyl Sulfides and Their Reactions with Olefinic Nucleophiles

2-Tributylstannyl-1,3-dithianes and 1-(tributylstannyl)alkyl sulfides are oxidized with ammonium hexanitratocerate(IV) or ferrocenium hexafluorophosphate to generate their cation radicals, which dissociate into the carbocations and tributylstannyl radical

Regio- and chemoselective conjugate 1,4-reduction of α-oxoketene dithioacetals with sodium borohydride and sodium cyanoborohydride

Theα-oxoketene dithioacetals 1 are shown to undergo conjugate 1,4-reduction in highly regio- and chemoselective manner with sodium borohydride in acetic acid to afford the corresponding β-oxodithioacetals 5 in good yields. These results have been rational