Highly regioselective 1,2-addition of alkoxybenzyl Grignard reagents to α-oxoketene dithioacetals: A facile regiocontrolled synthesis of alkoxynaphthalenes and their condensed analogs via aromatic annelation

Article abstract of DOI:10.1016/S0040-4020(99)00757-7

4-Methoxybenzyl- (A), 3,4-dimethoxybenzyl- (B) and 3,4- methylenedioxybenzyl- (C) Grignard reagents are shown to undergo regioselective 1,2-addition with various acyclic and cyclic α-oxoketene dithioacetals to afford carbinol dithioacetals which on BF