19064-89-2

Upstream product

• 5294-03-1 di-o-tolylethyne 
• 130818-18-7 2'-Methyl-2-methoxycarbonylacetylene 

Downstream Products

• 1361132-08-2 1,3-dimethyl-5-(2-(2-methylphenethyl)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 1361132-17-3 1',3'-dimethyl-3-o-tolyl-3,4-dihydro-1H,1'H-spiro[naphthalene-2,5'-pyrimidine]-2',4',6'(3'H)-trione 

Relevant academic research and scientific papers

Rapid access to 3-aryltetralin skeleton via C(sp3)-H bond functionalization: Investigation on the substituent effect of aromatic ring adjacent to C-H bond in hydride shift/cyclization sequence

The concise construction of 3-aryltetralin skeleton via hydride shift mediated C-H bond functionalization was achieved. In this process, the benzylic [1,5]-H shift occurred smoothly to furnish tetralin derivatives in good to excellent chemical yields. The electronic and steric properties of the aromatic ring adjacent to the C-H bond influenced significantly the reactivity of this transformation.