5294-03-1

Basic information

• Product Name: Benzene, 1,1'-(1,2-ethynediyl)bis[2-methyl-
• Synonyms: Benzene,1,1'-(1,2-ethynediyl)bis[2-methyl;di-o-tolylacetylene;bis-(o-tolyl)-acetylene;1,2-di-o-tolylethyne;2,2'-dimethyltolane;bis(2-methylphenyl)acetylene;1,2-di(2-methylphenyl)acetylene;1,2-di-o-tolylethyn
• CAS NO: 5294-03-1
• Molecular Formula: C16H14
• Molecular Weight: 206.287
• Mol File: 5294-03-1.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 338.481oC at 760 mmHg
• Flash Point: 151.297oC
• Density: 1.039g/cm3
• CAS DataBase Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2-methyl-(5294-03-1)
• EPA Substance Registry System: Benzene, 1,1'-(1,2-ethynediyl)bis[2-methyl-(5294-03-1)

Safety Data

• Hazardous Substances Data: 5294-03-1(Hazardous Substances Data)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 74-86-2 acetylene 
• 501-65-5 diphenyl acetylene 
• 74-88-4 methyl iodide 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 95-46-5 2-methylphenyl bromide 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 1066-54-2 trimethylsilylacetylene 
• 2093-46-1 2-methylphenyl diazonium tetrafluoroborate 
• 75-20-7 calcium carbide 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 16419-60-6 2-Methylphenylboronic acid 
• 471-25-0 Propiolic acid 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 

Downstream Products

• 10311-74-7 cis-2,2'-dimethylstilbene 
• 57542-62-8 4-Acetyl-2,2-dimethyldiphenylacetylen 
• 57542-61-7 4,4'-Diacetyl-2,2'-dimethyldiphenylacetylen 
• 62155-47-9 1,1,2-tri-o-tolylethene 
• 32383-75-8 (E)-2,3-di-o-tolylacrylic acid 

Relevant articles and documents

Synthesis of Diarylethynes from Aryldiazonium Salts by Using Calcium Carbide as an Alkyne Source in a Deep Eutectic Solvent

An efficient method for the synthesis of diarylethynes from aryldiazonium salts by using calcium carbide as an alkyne source at room temperature in a deep eutectic solvent is described. The salient features of this protocol are an inexpensive and easy-to-handle alkyne source, a nonvolatile and recyclable solvent, mild conditions, and a simple workup procedure.

Synthesis of α-Ketoimidoyl Fluorides via Geminal Fluorine-Promoted Azide Rearrangement

Despite the promising synthetic potential, the utilization of imidoyl fluorides has been hampered by the lack of broadly applicable preparative methods. Herein, bench-stable α-ketoimidoyl fluorides were synthesized from geminal chlorofluorides through tandem azidation/rearrangement under mild conditions. The efficiency was consistently high, regardless of the steric and electronic environments. The synthetic utility of the α-ketoimidoyl fluoride was also demonstrated. Furthermore, the remarkable accelerating effect of the geminal fluorine substituent was identified and rationalized by density functional theory calculation.

Rhodium-Catalyzed Regioselective Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes Using Formic Acid

A rhodium-catalyzed hydroformylation of alkynes with formic acid was developed. The method provides α,β-unsaturated aldehydes in high yield and E-selectivity without the need to handle toxic CO gas.