190669-12-6Relevant academic research and scientific papers
Highly linear selective cobalt-catalyzed addition of aryl imines to styrenes: Reversing intrinsic regioselectivity by ligand elaboration
Xu, Wengang,Yoshikai, Naohiko
supporting information, p. 14166 - 14170 (2015/02/19)
Highly linear selective, imine-directed hydroarylation of styrene has been achieved with cobalt-based catalytic systems featuring bis(2,4-dimethoxyphenyl)(phenyl)phosphine and either 2-methoxypyridine or DBU as a ligand and a Lewis base additive, respectively, thus affording a variety of 1,2-diarylethanes (bibenzyls) in good yields under mild reaction conditions. The triarylphosphine controls the regioselectivity, while the Lewis base significantly accelerates the reaction. Ligand screening and deuterium-labeling studies provide implications about the roles of the ligand and the Lewis base in the crucial C-C reductive elimination step.
Regioselectivity-switchable hydroarylation of styrenes
Gao, Ke,Yoshikai, Naohiko
supporting information; experimental part, p. 400 - 402 (2011/04/16)
Cobalt-phosphine and cobalt-carbene catalysts have been developed for the hydroarylation of styrenes via chelationassisted C-H bond activation, to afford branched and linear addition products, respectively, in a highly regioselective fashion. Deuterium-la
Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex
Martinez, Remi,Genet, Jean-Pierre,Darses, Sylvain
supporting information; experimental part, p. 3855 - 3857 (2009/02/07)
An efficient and practical catalytic system for the anti-Markovnikov ruthenium-catalyzed hydroarylation of styrenes with acetophenone, allowing a straightforward access to bibenzyl backbones, is described for the first time: this process, involving regios
Ruthenium-catalysed ortho alkylation of hydroxyacetophenones; the functionalisation of ring C aromatic diterpenoids
Harris, Paul W.R.,Woodgate, Paul D.
, p. 211 - 223 (2007/10/03)
Ortho C-H bond coupling of some 2-alkoxyacetophenones with olefins catalysed by ruthenium complexes results in a high yield of the ortho alkylated product, providing that a suitable protecting group is employed. No such protection was required for a para-alkoxy group; an activating effect was also observed. Bicyclic and tricyclic analogues react similarly.
