19075-45-7

Usage

Uses

Used in Pharmaceutical Industry:
6-BROMO-BENZO[B]THIOPHENE-2-CARBALDEHYDE is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a valuable building block in the development of new drugs with specific therapeutic properties.
Used in Chemical Research:
In the field of chemical research, 6-BROMO-BENZO[B]THIOPHENE-2-CARBALDEHYDE serves as a key compound for studying the reactivity and properties of aromatic and heterocyclic systems. Its synthesis and functionalization can provide insights into the development of new synthetic routes and methodologies.
Used in Biochemical Applications:
6-BROMO-BENZO[B]THIOPHENE-2-CARBALDEHYDE is used as an inhibitor of the lymphocyte pore-forming protein perforin. This application is particularly relevant in the study of immune system regulation and the development of therapeutic strategies for autoimmune diseases and other conditions involving the dysregulation of immune responses.

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 105191-64-8 6-Brombenzothiophen-2-carbonsaeure-ethylester 
• 374933-76-3 6-Brombenzothiophen-2-methanol 

Downstream Products

• 1190198-24-3 6-bromo-1-benzothiophene-2-carbonitrile 

Relevant academic research and scientific papers

Benzothiophene-flanked diketopyrrolopyrrole polymers: Impact of isomeric frameworks on carrier mobilities

Exploring new building blocks for solution-processable polymeric semiconductors has attracted much attention. We herein develop two isomeric benzothiophene-flanked diketopyrrolopyrrole polymers with different linkage positions and further systematically study the electronic structures, optical properties, and field-effect characteristics. Both polymers exhibit typical p-type transport characteristics with the highest mobility being up to 0.80 cm2 V-1 s-1. Our results suggest that the isomeric backbones for conjugated polymers greatly affect charge transport properties.

COMPOUNDS, PREPARATIONS AND USES THEREOF

The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as agents or drugs for inhibiting perforin activity and for treating a subject at risk of or susc

COMPOUNDS AND METHODS FOR MODULATING FXR

Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.