374933-76-3

Usage

Uses

Used in Organic Synthesis:
(6-Bromobenzo[b]thiophen-2-yl)methanol is used as a building block in organic synthesis for its ability to contribute to the formation of complex organic molecules. Its unique structure allows for the creation of a variety of compounds with different functionalities and properties.
Used in Pharmaceutical Research:
In pharmaceutical research, (6-Bromobenzo[b]thiophen-2-yl)methanol is utilized as a starting material for the development of new drugs. Its structural features make it a promising candidate for the design and synthesis of pharmaceutical agents with potential therapeutic applications.
Used in Materials Science:
(6-Bromobenzo[b]thiophen-2-yl)methanol may be employed in materials science due to its aromatic nature and potential electronic properties. It could be integrated into the development of new materials with specific electronic characteristics, such as in the creation of organic semiconductors or other advanced materials with tailored properties for various applications.

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 57848-46-1 4-bromo-2-fluorobenzaldehyde 
• 360576-01-8 6-bromo-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 105212-27-9 6-Brombenzothiophen-2-carbonylchlorid 
• 19075-58-2 6-bromo-1-benzothiophene-2-carboxylic acid 
• 5629-98-1 2,4-dibromobenzaldehyde 
• 105191-64-8 6-Brombenzothiophen-2-carbonsaeure-ethylester 
• 105191-52-4 5-(2,4-Dibrombenzyliden)-2-thioxothiazolidin-4-on 

Downstream Products

• 912332-92-4 6-bromo-2-methylbenzo[b]thiophene 
• 1133006-91-3 N-(4-methoxybenzyl)-N-((6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophen-2-yl)methyl)methanesulfonamide 
• 1132970-31-0 N-((6-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)benzo[b]thiophen-2-yl)methyl)methanesulfonamide 
• 1190198-24-3 6-bromo-1-benzothiophene-2-carbonitrile 
• 895550-11-5 6-bromo-2-(bromomethyl)benzo[b]thiophene 
• 19075-45-7 6-bromobenzo[b]thiophene-2-carbaldehyde 

Relevant academic research and scientific papers

Benzothiophene-flanked diketopyrrolopyrrole polymers: Impact of isomeric frameworks on carrier mobilities

Exploring new building blocks for solution-processable polymeric semiconductors has attracted much attention. We herein develop two isomeric benzothiophene-flanked diketopyrrolopyrrole polymers with different linkage positions and further systematically study the electronic structures, optical properties, and field-effect characteristics. Both polymers exhibit typical p-type transport characteristics with the highest mobility being up to 0.80 cm2 V-1 s-1. Our results suggest that the isomeric backbones for conjugated polymers greatly affect charge transport properties.

Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents That Selectively Detect Neurofibrillary Tangles in Alzheimers Disease Brains

In order to explore novel tau-imaging agents that can selectively detect neurofibrillary tangles in Alzheimers disease (AD) brains, we designed and synthesized a series of heterocyclic phenylethenyl and (3-pyridinyl)ethenyl derivatives with or without a dimethyl amino group. In in vitro autoradiography using AD brain sections, all radioiodinated ligands with a dimethyl amino group bound to Aβ deposits in the sections. In contrast, the ligands without a dimethyl amino group showed different patterns of radioactivity accumulation in the sections depending on the kind of heterocycle contained in their molecules. Particularly, a phenylethenyl benzimidazole derivative ([125I]64) showed marked radioactivity accumulation in the temporal lobe which corresponded with the distribution of tau deposits. [125I]64 also showed the most favorable pharmacokinetics in normal mouse brains (3.69 and 0.06% ID/g at 2 and 60 min postinjection, respectively) among all ligands in this study. Taken together, these results suggest that [123I]64 may be a new candidate tau-imaging agent.

Radioactive iodine labeled compound, and, radioactive pharmaceutical containing the same (by machine translation)

PROBLEM TO BE SOLVED: and compatibility and affinity for both amyloidosis acryloyldimethyltauric, labeled compd. radioactive iodine. SOLUTION: the present invention, N, N-labeled compd. dimethyl benzene amine including radioactive iodine or its salt. Selected drawing: no (by machine translation)

Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes Methods For Their Preparation And Their Use As Medicaments

The invention provides novel 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervo

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: Synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif

The synthesis and structure-activity relationships of a novel aryl uracil series which contains a fused 5,6-bicyclic ring unit for HCV NS5B inhibition is described. Several analogs display replicon cell culture potencies in the low nanomolar range along with excellent rat pharmacokinetic values.

Synthesis of a ferrocene-functionalized unsymmetrical benzo[b]thienyl- thienylethene photoswitch with a cyclopentene core

A new and potentially general synthetic route toward unsymmetrical benzo[b]thienyl-thienylethene compounds is described, with specific focus on conjugation of a ferrocene to the benzo[b]thiophene subunit. The route proceeds in an overall yield of 17%. Copyright

ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

COMPOUNDS AND METHODS FOR MODULATING FXR

Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Synthesis of Antileukemic Indolylvinyl-1-benzofurans and -benzothiophenes

2--1-benzofuran and -benzothiophene compounds 6-13 and 18-22 with terminal amidinium or imidazolinium groups were synthesized; in their antileukemic activity in mice they surpass the isosteric 2,2'-vinylenebis(1-benzofuran) and -(benzo-thiophene) compounds.