190777-66-3

Upstream product

• 57981-23-4 N-(cyclohex-1-en-1-ylmethyl)-4-methylbenzenesulfonamide 
• 208124-71-4 N-(2-Bromo-acetyl)-N-cyclohex-1-enylmethyl-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

Triethylborane-mediated atom-transfer cyclisation of 2-iodo-N-(prop-2-enyl)acetamides and related compounds

The 2-iodo-N-(prop-2-enyl)acetamides 1, upon treatment with triethylborane (0.2-0.6 mol equiv.) in boiling benzene, undergo iodine atom-transfer cyclisation to give the 4-(iodomethyl)pyrrolidin-2-ones 2 in high yields. The method has been applied to the synthesis of γ-lactones.