57981-23-4

Upstream product

• 4845-04-9 1-cyclohexene-1-methanol 
• 18448-47-0 methyl cyclohex-1-ene-1-carboxylate 
• 32917-19-4 cyclohex-1-en-1-ylmethylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 191595-69-4 N-tosyl-S-phenyl-S-(1-cyclohex-1-enylmethyl)sulfoximine 
• 591-49-1 1-methylcyclohex-1-ene 
• 851-06-9 bis(p-toluenesulfonyl) sulfur diimide 
• 42153-74-2 S-methyl-S-phenyl-N-(p-tolylsulfonyl)sulfoximide 
• 5330-61-0 1-nitromethyl-cyclohexene 
• 108-94-1 cyclohexanone 

Downstream Products

• 122419-42-5 4-Methyl-N-[(1S,6S)-1-(7-oxa-bicyclo[4.1.0]hept-1-yl)methyl]-N-[3-(toluene-4-sulfonyl)-propyl]-benzenesulfonamide 
• 122419-43-6 (5S,6S,7R)-2,5-Bis-(toluene-4-sulfonyl)-2-aza-spiro[5.5]undecan-7-ol 
• 122419-41-4 N-Cyclohex-1-enylmethyl-4-methyl-N-[3-(toluene-4-sulfonyl)-propyl]-benzenesulfonamide 
• 190777-66-3 N-Cyclohex-1-enylmethyl-N-(2-iodo-acetyl)-4-methyl-benzenesulfonamide 
• 208124-71-4 N-(2-Bromo-acetyl)-N-cyclohex-1-enylmethyl-4-methyl-benzenesulfonamide 
• 122419-44-7 N-(3-Bromo-propyl)-N-cyclohex-1-enylmethyl-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

Nickel-Catalyzed Mizoroki–Heck-Type Reactions of Unactivated Alkyl Bromides

The development of a general, nickel-catalyzed alkyl-Mizoroki–Heck reaction of unactivated alkyl bromides is described. The mild reaction proceeds efficiently using a wide range of primary and secondary alkyl bromides, and examples of intermolecular cross

Domino Aryne Annulation via a Nucleophilic-Ene Process

1,2-Benzdiyne equivalents possess the unique property that they can react with two arynophiles through iteratively generated 1,2- and 2,3-aryne intermediates. Upon rational modification on the second leaving group of these aryne precursors, a domino aryne annulation approach was developed through a nucleophilic-ene reaction sequence. Various benzo-fused N-heterocyclic frameworks were achievable under transition metal-free conditions with a broad substrate scope.

Catalytic Multisite-Selective Acetoxylation Reactions at sp2 vs sp3 C-H Bonds in Cyclic Olefins

The first Pd-catalyzed multisite-selective acetoxylation reactions are disclosed at an unactivated alkene sp2 C-H bond versus secondary allylic sp3 C-H bond in cyclic olefins via the modulation of directing groups. The different directing groups overcome the key challenge in differentiating C-H bonds and provide a new controlling approach for site-specific C-H activation. A wide variety of substrates are readily acetoxylated under operationally simple conditions. Mechanistic studies suggest that different Pd (IV) intermediates were involved in the multisite-selective acetoxylation reactions.

Palladium-catalyzed rearrangement of allylic sulfoximines: Application to the asymmetric synthesis of chiral allylic amines

The palladium(0)-catalyzed reactions of the primary and secondary allylic sulfoximines 7, 9, 11, 13, 15, 17, and 19 gives allylic sulfinamides without 1,3-allylic rearrangement. These compounds were not isolated but were converted to their corresponding N-tosyl allylic amines, primary and secondary 8, 10, 12, 14, 16, 18, and 20, respectively. In the case of the optically active secondary allylic sulfoximines 17 and 19, chiral N-tosyl allylic secondary amines were formed in high enantiomeric purities.