190788-61-5 Usage
Description
Coumarin-7-pinacolboronate is an off-white solid that is a derivative of coumarin, a naturally occurring organic compound found in a variety of plants. It is characterized by its unique chemical structure, which includes a boron atom bonded to a pinacol group and a coumarin moiety. Coumarin-7-pinacolboronate is known for its distinct chemical properties and potential applications in various fields.
Uses
Used in Chemical Sensing Applications:
Coumarin-7-pinacolboronate is used as a novel water-soluble fluorescent probe for detecting hydrogen peroxide. Its unique chemical structure allows it to selectively and sensitively respond to hydrogen peroxide, making it a valuable tool for monitoring this important analyte in various chemical and biological processes.
Used in Research and Development:
Due to its distinct chemical properties, Coumarin-7-pinacolboronate is also used in research and development for the synthesis of new compounds and materials. Its reactivity and versatility make it a promising candidate for the development of novel chemical entities with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Analytical Chemistry:
Coumarin-7-pinacolboronate can be employed as a reference material or standard in analytical chemistry for the calibration of instruments and the development of new analytical methods. Its well-defined chemical structure and properties make it suitable for use in the validation of analytical techniques and the establishment of quality control standards.
Check Digit Verification of cas no
The CAS Registry Mumber 190788-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,7,8 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 190788-61:
(8*1)+(7*9)+(6*0)+(5*7)+(4*8)+(3*8)+(2*6)+(1*1)=175
175 % 10 = 5
So 190788-61-5 is a valid CAS Registry Number.
190788-61-5Relevant articles and documents
Photocatalysis Enables Visible-Light Uncaging of Bioactive Molecules in Live Cells
Wang, Haoyan,Li, Wei-Guang,Zeng, Kaixing,Wu, Yan-Jiao,Zhang, Yixin,Xu, Tian-Le,Chen, Yiyun
supporting information, p. 561 - 565 (2019/01/04)
The photo-manipulation of bioactive molecules provides unique advantages due to the high temporal and spatial precision of light. The first visible-light uncaging reaction by photocatalytic deboronative hydroxylation in live cells is now demonstrated. Using Fluorescein and Rhodamine derivatives as photocatalysts and ascorbates as reductants, transient hydrogen peroxides were generated from molecular oxygen to uncage phenol, alcohol, and amine functional groups on bioactive molecules in bacteria and mammalian cells, including neurons. This effective visible-light uncaging reaction enabled the light-inducible protein expression, the photo-manipulation of membrane potentials, and the subcellular-specific photo-release of small molecules.
Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore
Du, Lupei,Li, Minyong,Zheng, Shilong,Wang, Binghe
, p. 3045 - 3048 (2008/09/20)
In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100-fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).
Synthesis of arylboronates via the palladium(0)-catalyzed cross-coupling reaction of tetra(alkoxo)diborons with aryl triflates
Ishiyama, Tatsuo,Itoh, Yoshiya,Kitano, Takahiro,Miyaura, Norio
, p. 3447 - 3450 (2007/10/03)
The cross-coupling reaction of (RO)2BB(OR)2 (RO = methoxo and pinacolato) with aryl triflates to give arylboronates was carried out at 80°C in the presence of PdCl2(dppf) (3 mol%), dppf (3 mol%) and KOAc (3 equivs) in dioxane. The reaction was available with various functional group such as nitro, cyano, ester, and carbonyl groups.
