190788-61-5Relevant articles and documents
Photocatalysis Enables Visible-Light Uncaging of Bioactive Molecules in Live Cells
Wang, Haoyan,Li, Wei-Guang,Zeng, Kaixing,Wu, Yan-Jiao,Zhang, Yixin,Xu, Tian-Le,Chen, Yiyun
supporting information, p. 561 - 565 (2019/01/04)
The photo-manipulation of bioactive molecules provides unique advantages due to the high temporal and spatial precision of light. The first visible-light uncaging reaction by photocatalytic deboronative hydroxylation in live cells is now demonstrated. Using Fluorescein and Rhodamine derivatives as photocatalysts and ascorbates as reductants, transient hydrogen peroxides were generated from molecular oxygen to uncage phenol, alcohol, and amine functional groups on bioactive molecules in bacteria and mammalian cells, including neurons. This effective visible-light uncaging reaction enabled the light-inducible protein expression, the photo-manipulation of membrane potentials, and the subcellular-specific photo-release of small molecules.
Rational design of a fluorescent hydrogen peroxide probe based on the umbelliferone fluorophore
Du, Lupei,Li, Minyong,Zheng, Shilong,Wang, Binghe
, p. 3045 - 3048 (2008/09/20)
In this study, we report a novel water-soluble umbelliferone-based fluorescent probe for hydrogen peroxide. This probe shows very large increases (up to 100-fold) in fluorescent intensity upon reaction with hydrogen peroxide, and good selectivity over other reactive oxygen species (ROS).
Synthesis of arylboronates via the palladium(0)-catalyzed cross-coupling reaction of tetra(alkoxo)diborons with aryl triflates
Ishiyama, Tatsuo,Itoh, Yoshiya,Kitano, Takahiro,Miyaura, Norio
, p. 3447 - 3450 (2007/10/03)
The cross-coupling reaction of (RO)2BB(OR)2 (RO = methoxo and pinacolato) with aryl triflates to give arylboronates was carried out at 80°C in the presence of PdCl2(dppf) (3 mol%), dppf (3 mol%) and KOAc (3 equivs) in dioxane. The reaction was available with various functional group such as nitro, cyano, ester, and carbonyl groups.