1908-90-3 Usage
Uses
Used in Pharmaceutical Research:
4-Phenyl-2-thiazolidinethione is utilized as a pharmaceutical candidate for its potential role in the treatment of type 2 diabetes. It is recognized for its ability to inhibit lipid peroxidation and enhance insulin sensitivity, which are crucial for managing diabetes and its complications.
Used in Synthesis of Pharmaceutical Compounds:
In the chemical industry, 4-Phenyl-2-thiazolidinethione serves as a valuable building block in the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a versatile component in the development of new drugs with diverse therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1908-90-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,0 and 8 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1908-90:
(6*1)+(5*9)+(4*0)+(3*8)+(2*9)+(1*0)=93
93 % 10 = 3
So 1908-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NS2/c11-9-10-8(6-12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,10,11)
1908-90-3Relevant academic research and scientific papers
Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase
Shankaran,Donnelly, Karla L.,Shah, Shrenik K.,Guthikonda, Ravindra N.,MacCoss, Malcolm,Humes, John L.,Pacholok, Stephen G.,Grant, Stephan K.,Kelly,Wong
, p. 4539 - 4544 (2007/10/03)
Syntheses and evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2- imines as inhibitors of nitric oxide synthase (NOS) are discussed. An extensive SAR was established for pyrrolidin-2-imines class of compounds. The amidines came out as the most potent inhibitors in addition to displaying selectivity.
STEREOSPECIFIC SYNTHESIS OF THIAZOLIDINE-2-THIONES
Brunet, Ernesto,Carreno, M. Carmen,Ruano, Jose Luis Garcia
, p. 1181 - 1195 (2007/10/02)
The synthesis of thiazolidine-2-thiones from vic-iodoalkanecarbamates, stereospecifically obtained from cis and trans-butene, is reported.Reaction of the iodo-derivatives with potassium ethylxanthate and sodium hydroxide, allowed the stereospecific format