190839-39-5

Basic information

• Product Name: diphenyl amino(4-chlorophenyl)methylphosphonate
• Synonyms: diphenyl amino(4-chlorophenyl)methylphosphonate
• CAS NO: 190839-39-5
• Molecular Formula: C₁₉H₁₇ClNO₃P
• Molecular Weight: 373.769941
• Mol File: 190839-39-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: diphenyl amino(4-chlorophenyl)methylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diphenyl amino(4-chlorophenyl)methylphosphonate(190839-39-5)
• EPA Substance Registry System: diphenyl amino(4-chlorophenyl)methylphosphonate(190839-39-5)

Safety Data

• Hazardous Substances Data: 190839-39-5(Hazardous Substances Data)

Upstream product

• 164065-24-1 [benzyloxycarbonylamino-(4-chloro-phenyl)-methyl]-phosphonic acid diphenyl ester 
• 104-88-1 4-chlorobenzaldehyde 
• 4712-55-4 diphenyl hydrogen phosphite 
• 106787-29-5 diphenyl [(amino)(p-chlorophenyl)methyl]phosphonate hydrobromide 

Downstream Products

• 1403781-81-6 diphenyl ((4-chlorophenyl)(isothiocyanato)methyl)phosphonate 
• 254982-97-3 [(4-chloro-phenyl)-isocyanato-methyl]-phosphonic acid diphenyl ester 

Relevant articles and documents

Synthesis of phosphonodipeptide conjugates of ursolic acid and their homologs

To prepare novel derivatives of naturally bioactive 3β-hydroxy-urs-12- en-28-oic acid (ursolic acid) with unusual properties and broad spectrum of activities, a number of chemical reactions were conducted. First, a variety of a-aminophosphonates were prepared by a series of reactions involving the three-component Mannich type reaction as a key step. Second, an array of phosphonodipeptides and their homologs was synthesized through multistep reactions including condensation of phthalic anhydride with glycine or β-alanine, chlorination of N-blocked amino acids, coupling of acid chloride with α-aminophosphonates and sequential hydrazinolysis. Finally, new classes of phosphonodipeptide conjugates of ursolic acid and their homologs were obtained by condensation of 3β-acetoxy-urs-12-en-28-oyl chloride with phosphonodipeptides and their homologs.