190850-37-4

Basic information

• Product Name: 2-(4-CHLOROBENZOYL)PYRIDINE
• Synonyms: 2-(4-CHLOROBENZOYL)PYRIDINE;4-(2-Pyridinyl)benzoyl Chloride;4-(Pyridin-2-yl)benzoyl Chloride
• CAS NO: 190850-37-4
• Molecular Formula: C₁₂H₈ClNO
• Molecular Weight: 217.65
• EINECS: 228-662-8
• Product Categories: Aromatics;Heterocycles;Intermediates
• Mol File: 190850-37-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 356°C at 760 mmHg
• Flash Point: 169.1°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 3E-05mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: 2-(4-CHLOROBENZOYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROBENZOYL)PYRIDINE(190850-37-4)
• EPA Substance Registry System: 2-(4-CHLOROBENZOYL)PYRIDINE(190850-37-4)

Safety Data

• Hazardous Substances Data: 190850-37-4(Hazardous Substances Data)

Usage

Uses

An intermediate in the preparation of α7 nicotinic acetylcholine receptor agonist as well as glycine transporter inhibitors.

InChI:InChI=1/C12H8ClNO/c13-10-6-4-9(5-7-10)12(15)11-3-1-2-8-14-11/h1-8H

Upstream product

• 14047-29-1 4-carboxyphenylboronic acid 
• 109-04-6 2-bromo-pyridine 
• 4385-62-0 4-(pyridin-2-yl)benzoic acid 
• 4467-06-5 2-(4-methylphenyl)pyridine 

Downstream Products

• 1332585-85-9 3-(5-(4-(pyridin-2-yl)phenyl)-1,3,4-oxadiazol-2-yl)-9-hexyl-9H-carbazole 
• 1175529-94-8 methyl 2-hydroxy-3-(4-(pyridin-2-yl)benzamido)benzoate 
• 717116-23-9 N-(4-tert-butyl-phenyl)-4-pyridin-2-yl-benzamide 
• 1380546-82-6 N-methoxy-4-(pyridin-2-yl)benzamide 
• 1338816-29-7 C₂₄H₂₃F₂N₃O₂ 
• 1338816-28-6 C₂₅H₂₃F₂N₃O₃ 
• 1338816-27-5 C₂₅H₂₃F₂N₃O₃ 
• 1338816-26-4 C₂₃H₂₁F₂N₃O₂ 
• 190850-38-5 C₁₄H₁₄N₂O₂ 

Relevant articles and documents

Ammonia as Ultimate Amino Source in Synthesis of Primary Amines via Nickel-Promoted C-H Bond Amination

The direct use of ammonia in transition-metal promoted C-H bond amination for the synthesis of primary amines is considered to be one of the major challenges in synthetic organic chemistry. Herein, we report that such transformation can be successfully ac

Novel yellow phosphorescent iridium complexes containing a carbazole-oxadiazole unit used in polymeric light-emitting diodes

Yellow iridium complexes Ir(PPOHC)3 and (PPOHC) 2Ir(acac) (PPOHC: 3-(5-(4-(pyridin-2-yl)phenyl)-1,3,4-oxadiazol-2-yl) -9-hexyl-9H-carbazole) were synthesized and characterized. The Ir(PPOHC) 3 complex has good thermal stability with 5% weight-reduction occurring at 370 °C and a glass-transition temperature of 201 °C. A polymeric light-emitting diode using the Ir(PPOHC)3 complex as a phosphorescent dopant showed a luminance efficiency of 16.4 cd/A and the maximum external quantum efficiency of 6.6% with CIE coordinates of (0.50, 0.49). A white polymeric light-emitting diode was fabricated using Ir(PPOHC)3 which showed a luminance efficiency of 15.3 cd/A, with CIE coordinates of (0.39, 0.44). These results indicate that the iridium complexes containing a linked carbazole-oxadiazole unit are promising candidates in high-efficiency electroluminescent devices.

Azapeptide derivatives as HIV protease inhibitors

This invention relates to novel compounds of the Formula Ib: that are azapeptides, and pharmaceutically acceptable salts thereof. More specifically, the invention relates to novel azapeptide compounds that are derivatives of the HIV protease inhibitor atazanavir sulfate. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and a carrier, and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administering HIV protease inhibitors. The invention also relates to the use of one or more of the disclosed compounds as reagents in analytical studies involving atazanavir.