190852-37-0 Usage
Uses
Used in Biochemical Research:
NEOPENTYL METHANTHIOSULFONATE is used as a probe for [studying protein structures and functions] because of its ability to react specifically and rapidly with thiols to form mixed disulfides.
Used in Pharmaceutical Industry:
NEOPENTYL METHANTHIOSULFONATE is used as a tool for [mapping the pore-lining regions of various receptors] such as the ACh receptor channel, the GABA receptor channel, and lactose permease. This application aids in understanding the structural and functional aspects of these receptors, which can be crucial for the development of targeted drugs and therapies.
Used in Molecular Biology:
NEOPENTYL METHANTHIOSULFONATE is used as a reagent for [investigating protein-protein interactions and protein conformational changes] due to its thiol-reactive properties. This can be particularly useful in studying the mechanisms of protein folding, stability, and interactions with other biomolecules.
Check Digit Verification of cas no
The CAS Registry Mumber 190852-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,8,5 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 190852-37:
(8*1)+(7*9)+(6*0)+(5*8)+(4*5)+(3*2)+(2*3)+(1*7)=150
150 % 10 = 0
So 190852-37-0 is a valid CAS Registry Number.
190852-37-0Relevant academic research and scientific papers
Chemically modified enzymes
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, (2008/06/13)
Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected from the group consisting of: a) —SR1R2, wherein R1is an alkyl and R2is a charged or polar moiety; b) —SR3, wherein R3is a substituted or unsubstituted phenyl; c) —SR4, wherein R4is substituted or unsubstituted cyclohexyl; d) —SR5, wherein R5is C10-C15alkyl; and e) —SR6wherein R6is a C1-6alkyl. Also, methods of producing the modified enzymes are provided, as well as detergent and feed additives and a composition for the treatment of a textile. A method for using the modified enzymes in organic synthesis is additionally provided. Further, modified enzymes having improved activity, altered pH profile and/or wash performance are provided.
