190896-56-1

Upstream product

• 80904-75-2 4-hydroxymethyl-5H-furan-2-one 
• 190896-38-9 (E)-2-Benzyloxymethyl-but-2-ene-1,4-diol 
• 133435-76-4 4-(benzyloxymethyl)-2(5H)-furanone 
• 77356-33-3 4-acetoxy-3-acetoxymethyl-but-2-enoic acid ethyl ester 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 190896-54-9 (E)-2-Benzyloxymethyl-4-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-but-2-en-1-ol 

Downstream Products

• 190896-64-1 (2S,3S)-2-Benzyloxymethyl-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-oxirane-2-carbaldehyde 
• 190896-58-3 ((2S,3S)-3-Benzyloxymethyl-3-vinyl-oxiranylmethoxy)-dimethyl-(1,1,2-trimethyl-propyl)-silane 
• 190896-36-7 ((2S,3S)-3-Benzyloxymethyl-3-vinyl-oxiranyl)-methanol 

Relevant academic research and scientific papers

Methylation-ring opening of 3,3-disubstituted 2,3-epoxy alcohols. Synthesis of chiral quaternary fragments for assembly of briaran diterpenes

Two chiral quaternary carbon-containing fragments suitable for elaboration to the briaran diterpenes were obtained by regioselective methylation of functionalized 3,3-disubstituted 2,3-epoxy-1-ols. The factors which favor methylation at the more hindered position of a trisubstituted 2,3-epoxy alcohol were determined.