190902-21-7

Basic information

• Product Name: (3S,4R,5RS)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-cyano-2-pyrrolidinone
• CAS NO: 190902-21-7
• Molecular Weight: 350.371
• Mol File: 190902-21-7.mol

Chemical Properties

• CAS DataBase Reference: (3S,4R,5RS)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-cyano-2-pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R,5RS)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-cyano-2-pyrrolidinone(190902-21-7)
• EPA Substance Registry System: (3S,4R,5RS)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-cyano-2-pyrrolidinone(190902-21-7)

Safety Data

• Hazardous Substances Data: 190902-21-7(Hazardous Substances Data)

Upstream product

• 190902-20-6 (1RS,2S,3R)-2,3-bis(methoxymethyl)oxy-4-hydroxy-1-cyano-N-(4-methoxybenzyl)butanamide 
• 166542-98-9 (2R,3R)-2,3-bis(methoxymethoxy)-4-<(t-butyldimethylsilyl)oxy>-1-butanol 
• 190902-19-3 (1RS,2S,3R)-2,3-bis(methoxymethyl)oxy-4-(t-butyldimethylsilyl)oxy-1-cyano-N-(4-methoxybenzyl)butanamide 
• 166542-99-0 (2S,3R)-2,3-bis(methoxymethoxy)-4-<(t-butyldimethylsilyl)oxy>butanal 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 190902-22-8 (3S,4R,5RS)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-methoxycarbonyl-2-pyrrolidinone 
• 108692-47-3 (2R,3R,4R)-2-hydroxymethyl-3,4-dihydro-2H-pyrrole-3,4-diol 
• 139877-36-4 (3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-one 
• 190902-34-2 (3S,4R,5S)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-hydroxymethyl-2-pyrrolidinone 
• 190902-23-9 (3S,4R,5R)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-hydroxymethyl-2-pyrrolidinone 
• 190902-30-8 (3S,4R,5S)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 190902-25-1 (3S,4R,5R)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 190902-27-3 (3S,4R,5R)-N-(t-butoxycarbonyl)-2-hydroxy-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)pyrrolidine 
• 190902-32-0 (3S,4R,5S)-N-(t-butoxycarbonyl)-2-hydroxy-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)pyrrolidine 
• 190902-26-2 (3S,4R,5R)-N-(t-butoxycarbonyl)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 190902-31-9 (3S,4R,5S)-N-(t-butoxycarbonyl)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 190902-24-0 (3S,4R,5R)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 190902-29-5 (3S,4R,5S)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-(t-butyldiphenylsiloxymethyl)-2-pyrrolidinone 
• 245484-40-6 (3S,4R,5R)-N-(4-methoxybenzyl)-3,4-bis(methoxymethyl)oxy-5-methyl-2-pyrrolidinone 

Relevant articles and documents

Synthesis of nectrisine and related compounds, and their biological evaluation

An efficient and novel process is described for the synthesis of nectrisine 5 and its related derivatives 6,7 as potent glucosidase inhibitors via the corresponding lactams starting from D-(-)-diethyl tartrate. Also the results of biological evaluation of the synthesized compounds are described.

Novel synthesis of nectrisine and 4-epi-nectrisine

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