190912-79-9Relevant academic research and scientific papers
Poly-L-leucine catalysed epoxidation reactions: A short, stereoselective route to chiral α,β-epoxyalcohols
Gillmore, Adam T.,Roberts, Stanley M.,Hursthouse, Mike B.,Abdul Malik
, p. 3315 - 3318 (1998)
Grignard alkylation of epoxyketones (1), (4) from Poly-L-leucine catalysed asymmetric epoxidation of α,β-unsaturated ketones provides a short, stereocontrolled route to optically pure α,β-epoxy tertiary alcohols (2), (3). These epoxyalcohols undergo Payne
Polyamino acids as catalysts in asymmetric synthesis
Porter, Michael J.,Roberts, Stanley M.,Skidmore, John
, p. 2145 - 2156 (2007/10/03)
The use of polyamino acids in asymmetric organic synthesis is reviewed. Particular emphasis is placed on the asymmetric epoxidation of α,β- unsaturated ketones with hydrogen peroxide in the presence of polyalanine or polyleucine, and further transformatio
Asymmetric epoxidation of enones employing polymeric α-amino acids in non-aqueous media
Bentley, Paul A.,Bergeron, Sophie,Cappi, Michael W.,Hibbs, David E.,Hursthouse, Michael B.,Nugent, Thomas C.,Pulido, Rosalino,Roberts, Stanley M.,Wu, L. Eduardo
, p. 739 - 740 (2007/10/03)
Urea-hydrogen peroxide complex in an organic solvent and in the presence of DBU and poly-(L)leucine causes rapid asymmetric epoxidation of the enones 1a, b and d.
