190972-89-5

Upstream product

• 916888-57-8 2-acetyl-3,5-dimethoxy-6-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)phenyl 2-chlorobenzoate 
• 609-65-4 o-chlorobenzoyl chloride 
• 113225-07-3 1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 190973-17-2 1-(3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2-hydroxy-4,6-dimethoxyphenyl)ethanone 
• 1445-73-4 1-Methyl-4-piperidone 
• 500-99-2 3,5-dimethoxyphenol 
• 190973-16-1 3,5-dimethoxy-2-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenol 

Relevant academic research and scientific papers

Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site

The bioactivity in hepatocytes of glycogen phosphorylase inhibitors that bind to the active site, the allosteric activator site and the indole carboxamide site has been described. However, the pharmacological potential of the purine nucleoside inhibitor s

Structure-activity relationship studies of flavopiridol analogues

Cyclin dependent kinases (CDKs) along with the complementary cyclins form key regulatory checkpoint controls on the cell cycle. Flavopiridol is a synthetic flavone that shows potent and selective cyclin-dependent kinase inhibitory activity. In this paper, we report modifications of the 3-hydroxy-1-methylpiperidinyl (D ring) of flavopiridol and their effect on CDK inhibitory activity. (C) 2000 Elsevier Science. All rights reserved.