191017-55-7Relevant academic research and scientific papers
The synthesis of dienecarbamates as adapt prodrug models
Ma, G. Xiaobo,Batey, Robert A.,Taylor, Scott D.,Hum, Gabriel,Jones, J. Bryan
, p. 2445 - 2453 (2007/10/03)
An efficient process utilizing a modified Curtius rearrangement was developed for the synthesis of carbamate substrates 1a-c and 2. The potential of these compounds as prodrug structures 3 for antibody-directed abzyme prodrug therapy (ADAPT) has been chem
