191017-56-8Relevant academic research and scientific papers
HISTONE DEACETYLASE INHIBITORS
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, (2008/06/13)
The present invention provides histone deacetylase inhibitors of general formula (I), process for the preparation of such compounds and uses of the compounds in medicine.
The synthesis of dienecarbamates as adapt prodrug models
Ma, G. Xiaobo,Batey, Robert A.,Taylor, Scott D.,Hum, Gabriel,Jones, J. Bryan
, p. 2445 - 2453 (2007/10/03)
An efficient process utilizing a modified Curtius rearrangement was developed for the synthesis of carbamate substrates 1a-c and 2. The potential of these compounds as prodrug structures 3 for antibody-directed abzyme prodrug therapy (ADAPT) has been chem
