191042-20-3Relevant academic research and scientific papers
Simple amphiphilic isosteviol-proline conjugates as chiral catalysts for the direct asymmetric aldol reaction in the presence of water
An, Ya-Jie,Zhang, Yun-Xiao,Wu, Ya,Liu, Zhao-Min,Pi, Chao,Tao, Jing-Chao
, p. 688 - 694 (2010)
Two novel amphiphilic catalysts 3 and 4 were synthesized by the condensation of isosteviol with l-proline in a one-pot process. With only 1 mol % loading, the catalyst 3 showed excellent activity (up to >99% yield) and stereoselectivity (up to 99:1 dr, >9
Phthalimido-prolinamide: A new chiral catalyst for solvent free enantioselective aldol reactions
Kumar, Togapur Pavan,Vavle, Namdevrao Chethan,Patro, Vidyavathi,Haribabu, Kothapalli
, p. 457 - 461 (2014/04/17)
A new prolinamide derivative phthalimido-prolinamide 1 was developed for organocatalytic enantioselective direct aldol reactions of various aldehydes with ketones. The catalytic protocol is effective with 15 mol % of catalyst under solvent free and additi
N-Prolinylanthranilic acid derivatives as bifunctional organocatalysts for asymmetric aldol reactions
Pearson, Anthony J.,Panda, Santanu
experimental part, p. 3969 - 3975 (2011/06/24)
Several N-prolinylanthranilic acid derivatives were prepared and tested as bifunctional organocatalysts in the direct asymmetric aldol reaction of cyclohexanone with p-nitrobenzaldehyde. It was found that methyl substitution ortho to the carboxylic acid i
