191090-29-6

Basic information

• Product Name: (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI&
• Synonyms: (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI&;(S)-(-)-5,5-DIPHENYL-4-METHYL-2-OXAZOLID;(S)-4-Methyl-5,5-diphenyloxazolidin-2-one;(S)-5,5-Diphenyl-4-methyl-2-oxazolidinone,99%e.e.;(4S)-4-methyl-5,5-diphenyl-1,3-oxazolidin-2-one
• CAS NO: 191090-29-6
• Molecular Formula: C₁₆H₁₅NO₂
• Molecular Weight: 253.299
• Product Categories: Asymmetric Synthesis;Chiral Auxiliaries;Oxazolidinone Derivatives
• Mol File: 191090-29-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 263-267 °C(lit.)
• Boiling Point: 464.953 °C at 760 mmHg
• Flash Point: 234.995 °C
• Appearance: /
• Density: 1.156 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI&(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI&(191090-29-6)
• EPA Substance Registry System: (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI&(191090-29-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 191090-29-6(Hazardous Substances Data)

Usage

General Description

S)-(-)-5,5-Diphenyl-4-methyl-2-oxazol is a chemical compound that belongs to the oxazol family. (S)-(-)-5 5-DIPHENYL-4-METHYL-2-OXAZOLI& is a chiral molecule, meaning it has a non-superimposable mirror image, and the (S)-(-) form indicates that it has a specific spatial arrangement of atoms. It is commonly used in organic synthesis and as a chiral auxiliary in asymmetric synthesis. The oxazol ring in this compound provides a versatile functional group for the formation of new carbon-carbon bonds, making it valuable for creating complex organic molecules. (S)-(-)-5,5-Diphenyl-4-methyl-2-oxazol has applications in pharmaceuticals, agrochemicals, and materials science due to its ability to impart specific stereochemical properties to molecules.

InChI:InChI=1/C16H15NO2/c1-12-16(19-15(18)17-12,13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-12H,1H3,(H,17,18)/t12-/m0/s1

Upstream product

• 78603-91-5 (S)-2-amino-1,1-diphenylpropan-1-ol 
• 503-38-8 trichloromethyl chloroformate 
• 42746-51-0 5,5-diphenyl-4-methyl-2-oxazolidinone 
• 124-38-9 carbon dioxide 
• 98-59-9 p-toluenesulfonyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 290351-99-4 (S)-2-Fluoro-1-methyl-2,2-diphenyl-ethylamine 
• 67659-37-4 (S)-1,1-diphenyl-2-aminopropane 

Relevant articles and documents

Synthesis and application of N-3,5-dinitrobenzoyl and C3 symmetric diastereomeric chiral stationary phases

Three diastereomeric chiral compounds, namely, (R,R)-(+)-2-amino-1,2-diphenylethanol, (1S,2R)-(+)-2-amino-1,2-diphenylethanol, and (1R,2R)-(+)-1,2-diphenylethylenediamine were used as starting materials for preparing three N-3,5-dinitrobenzoyl derivative

Synthesis of chiral oxazolidin-2-ones by 1,2-amino alcohols, carbon dioxide and electrogenerated acetonitrile anion

An improved electrochemical synthesis of chiral oxazolidin-2-ones from chiral 1,2-amino alcohols is obtained by direct electrolysis of solutions of MeCN-TEAP containing the amino alcohol, with subsequent CO2 bubbling and addition of TsCl. This

Synthesis of chiral oxazolidin-2-ones and imidazolidin-2-ones via DMAP- catalyzed isocyanation of amines with di-tert-butyl dicarbonate

Oxazolidin-2-ones and imidazolidin-2-ones are prepared under mild reaction conditions by DMAP-catalyzed isocyanation of 1,2-aminoalcohols and 1,2-diamines with di-tert-butyl dicarbonate and subsequent cyclization.