191090-77-4Relevant academic research and scientific papers
Crystal engineering for absolute asymmetric synthesis through the use of meta substituted aryl groups
Wu, Lian-Chung,Cheer, Clair J.,Olovsson, Gunnar,Scheffer, John R.,Trotter, James,Wang, Sue-Lein,Liao, Fen-Ling
, p. 3135 - 3138 (1997)
A significant tendency towards crystallization in chiral space groups has been found for 4-benzyloxy-2-pyridones whose phenyl groups are meta-substituted (m-Cl, m-Br, m-Me and m-OMe). Irradiation of single crystals of three of these materials leads to optically active p-lactam derivatives in high chemical and optical yields via an allowed disrotatory electrocyclization.
