191092-07-6

Basic information

• Product Name: (R)-3-(Tosyloxymethyl)-N-Boc-piperidine
• Synonyms: 1-Piperidinecarboxylicacid, 3-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, 1,1-dimethylethyl ester,(R)-; (R)-1-tert-Butoxycarbonyl-3-(p-toluenesulfonyloxymethyl)piperidine;1,1-Dimethylethyl(3R)-3-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-piperidinecarboxylate
• CAS NO: 191092-07-6
• Molecular Formula: C₁₈H₂₇NO₅S
• Molecular Weight: 369.48
• Mol File: 191092-07-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-(Tosyloxymethyl)-N-Boc-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(Tosyloxymethyl)-N-Boc-piperidine(191092-07-6)
• EPA Substance Registry System: (R)-3-(Tosyloxymethyl)-N-Boc-piperidine(191092-07-6)

Safety Data

• Hazardous Substances Data: 191092-07-6(Hazardous Substances Data)

Usage

General Description

(R)-3-(Tosyloxymethyl)-N-Boc-piperidine is a chemical compound that consists of a piperidine ring with a tosyloxymethyl group and a Boc protecting group. The tosyloxymethyl group is a derivative of toluenesulfonyl group and is commonly used as a leaving group in organic synthesis. The Boc protecting group is often used to protect amines from undesired reactions in organic chemistry. (R)-3-(Tosyloxymethyl)-N-Boc-piperidine is commonly used as a building block in the synthesis of various pharmaceuticals and other organic compounds. Its unique structure and reactivity make it a valuable tool in the field of organic chemistry.

Upstream product

• 4124-41-8 p-toluenesulfonylanhydride 
• 116574-71-1 tert-butyl (3R)-3-(hydroxymethyl)piperidine-1-carboxylate 
• 25137-01-3 (R)-ethyl nipecotate 
• 37675-20-0 (R)-3-hydroxymethyl piperidine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1187465-61-7 (R,Z)-tert-butyl 3-((5-tert-butyl-2-(5-chloro-2-methoxybenzoylimino)thiazol-3(2H)-yl)methyl)piperidine-1-carboxylate 
• 1393331-68-4 C₂₁H₂₂BrFN₄O₂ 
• 1393331-70-8 (R)-N-(4-bromo-2-fluorophenyl)-7-((1-(2-fluoroethyl)piperidin-3-yl)methoxy)-6-methoxyquinazolin-4-amine 
• 1393331-67-3 [18F](R)-N-(4-bromo-2-fluorophenyl)-7-((1-(2-fluoroethyl)piperidin-3-yl)methoxy)-6-methoxyquinazolin-4-amine 
• 1093988-80-7 1,1-dimethylethyl (3R)-3-[({4-[5-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}methyl)-1,3,4-oxadiazol-2-yl]-3-methylphenyl}oxy)methyl]-1-piperidinecarboxylate 

Relevant articles and documents

Synthesis and in vitro evaluation of [18F](R)-FEPAQ: A potential PET ligand for VEGFR2

Synthesis and in vitro evaluation of [18F](R)-N-(4-bromo-2- fluorophenyl)-7-((1-(2-fluoroethyl)piperidin-3-yl)methoxy)-6-methoxyquinazolin- 4-amine ((R)-[18F]FEPAQ or [18F]1), a potential imaging agent for the VEGFR2, usin

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

Disclosed herein are compounds of formula (I) wherein R1, R2, R3, R25a, R26a, X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described

Novel Compounds

Compounds of Formulae I, or pharmaceutically acceptable salts thereof: wherein X, R1, R2 and R3 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.