191105-59-6

Basic information

• Product Name: (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one
• Synonyms: (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one
• CAS NO: 191105-59-6
• Molecular Weight: 249.266
• Mol File: 191105-59-6.mol

Chemical Properties

• CAS DataBase Reference: (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one(191105-59-6)
• EPA Substance Registry System: (S)-N-propionyl-4-(4-hydroxybenzyl)oxazolidin-2-one(191105-59-6)

Safety Data

• Hazardous Substances Data: 191105-59-6(Hazardous Substances Data)

Upstream product

• 123-62-6 propionic acid anhydride 
• 187332-12-3 (4S)-4-(4-hydroxybenzyl)-1,3-oxazolidin-2-one 
• 4122-52-5 1-(1H-imidazol-1-yl)propan-1-one 
• 170438-03-6 (S)-4-(4-(benzyloxy)benzyl)oxazolidin-2-one 
• 66605-58-1 O-benzyl N-Boc-L-tyrosinol 
• 85803-44-7 (S)-2-amino-3-(4-benzyloxyphenyl)-1-propanol 
• 2130-96-3 O-benzyl-N-tert-butoxycarbonyl-L-tyrosine 
• 191105-60-9 (S)-4-(4-Benzyloxy-benzyl)-3-propionyl-oxazolidin-2-one 

Downstream Products

• 7384-80-7 (S)-2-methyl-3-phenylpropan-1-ol 
• 77943-96-5 (2R)-2-methyl-3-phenyl-1-propanol 
• 63930-46-1 3-(benzyloxy)-2-methylpropan-1-ol 

Relevant articles and documents

Chemoselective N-acylation of indoles and oxazolidinones with carbonylazoles

Unique reactivity: In the presence of more reactive amine and alcohol functional groups and of carboxylic acids, the chemoselective N-acylation of indoles (see scheme) and oxazolidinones is achieved by taking advantage of the unique reactivity of carbonylazole acylating agents with catalytic amounts of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). Copyright

A cleavable linker strategy for optimising enolate alkylation reactions of a polymer-supported Evans' oxazolidin-2-one

A cleavable linker strategy has been used to optimise the enolate alkylation reactions of a recyclable l-tyrosine derived polymer-supported oxazolidin-2-one for the asymmetric synthesis of a series of chiral α-alkyl acids. The Royal Society of Chemistry.

Resin type can have important effects on solid phase asymmetric alkylation reactions

A new N-propionylated oxazolidinone 1 is prepared; asymmetric alkylations of this auxiliary proceed with varying yields and enantioselectivities when supported on Merrifield, Wang and TentaGel R PHB resins.