19111-20-7Relevant articles and documents
Nitroimidazole compound as well as preparation method and application thereof
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Paragraph 0037-0042, (2020/01/11)
The invention discloses a nitroimidazole compound, particularly discloses a compound shown as a formula (I), and further discloses a preparation method of the compound and application of the compoundin preparation of medicines for treating diseases relate
Converting urea into high value-added 2-oxazolidinones under solvent-free conditions
Wang, Peixue,Li, Qinghe,Liu, Shimin,Deng, Youquan
, p. 94382 - 94386 (2016/10/21)
Zn-modified mesoporous Mg-Al nanoplates oxides were prepared by co-precipitation and further characterized and used in the synthesis of 2-oxazolidinones from urea and epoxides under solvent-free conditions. The characterization results suggested that Zn1.1Mg2.0AlO4.6, which featured more accessible active medium basic sites, were favorable for obtaining superior catalytic activity. This synthetic process is mild, convenient, simple and gives good yields up to 80%.
Efficient synthesis of 2-oxazolidinones from epoxides and carbamates catalyzed by amine-functionalized ionic liquids
Shang, Jianpeng,Li, Zuopeng,Su, Caina,Guo, Yong,Deng, Youquan
, p. 71765 - 71769 (2015/09/08)
A series of amine-functionalized ionic liquids were prepared and their catalytic performance was tested in the synthesis of 2-oxazolidinones from epoxides and carbamates. Under optimized reaction conditions, good to excellent yields of various 2-oxazolidinones were achieved with different epoxides and carbamates. Moreover, the amine-functionalized ionic liquid catalyst could be easily recovered and reused without significant loss in activity.
Efficient synthesis of 2-oxazolidinone from epoxides and carbamates with binary MgFe oxides as a magnetic solid base catalyst
Shang, Jianpeng,Liu, Shimin,Lu, Liujin,Ma, Xiangyuan,He, Yude,Deng, Youquan
, p. 13 - 17 (2013/01/14)
Magnetic binary MgFe oxides were prepared by co-precipitation method, characterized and tested in the synthesis of 2-oxazolidinones from epoxides and carbamates. The catalytic results showed that the catalyst with Mg/Fe molar ratio of 1 and calcined at 400°C exhibited superior catalytic activity. The catalyst could be magnetically separated, recycled and reused for five runs without noticeable deactivation. Under the optimized conditions, various 2-oxazolidinones derivatives were successfully synthesized with good to excellent isolated yields.
GSK-3BETA INHIBITOR
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Page/Page column 30, (2011/04/13)
For the purpose of providing a GSK-3β inhibitor containing a 2-aminopyridine compound or a salt thereof or a prodrug thereof useful as an agent for the prophylaxis or treatment of a GSK-3β-related pathology or disease, the present invention provides a GSK-3β inhibitor containing a compound represented by the formula (IA): wherein each symbol is as defined in the specification. or a salt thereof or a prodrug thereof.
Facile one-pot synthesis of oxazolidin-2-ones from phenyl 2-hydroxyalkyl selenides
Sheng, Shou-Ri,Luo, Hai-Rong,Huang, Zhen-Zhong,Sun, Wu-Kang,Liu, Xiao-Ling
, p. 2693 - 2699 (2008/02/12)
A novel, convenient, efficient, three-step, one-pot synthesis of 2-oxazolidinones from phenyl 2-hydroxyalkyl selenides was developed. Using this methodology, 2-oxazolidinones are obtained in good yields (76-85%) by reaction of phenyl 2-hydroxyalkyl seleni
A facile one-pot solid-phase synthesis of oxazolidin-2-ones using polymer-supported 2-hydroxyalkyl selenide reagent
Hu, Qiao-Sheng,Sheng, Shou-Ri,Lin, Shu-Ying,Wei, Mei-Hong,Xin, Qin,Liu, Xiao-Ling
, p. 74 - 75 (2008/02/04)
A simple, efficient and environmentally friendly procedure for one-pot solid-phase synthesis of 2-oxazolidinones in moderate to good yields by reaction of polystyrene-supported 2-hydroxyalkyl selenide with benzoyl isocyanate and subsequent oxidation/cycli
Thiazolidine and oxazolidine derivatives, their preparation and their medical use
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, (2008/06/13)
Compounds of formula (I): STR1 and salts, esters and solyates thereof and pro-drugs therefor are useful for the treatment and/or prophylaxis of a variety of disorders, including one or more of: hyperlipemia, hyperglycemia, obesity, glucose tolerance insufficiency, insulin resistance and diabetic complications.
RECYCLIZATION REACTIONS OF SMALL RINGS. 8. SYNTHESIS OF 5-SUBSTITUTED 2-OXAZOLIDONES FROM THIAZOLIDINE-2,4-DIONE AND OXIRANES
Korotkikh, N. I.,Aslanov, A. F.,Shvaika, O. P.
, p. 915 - 917 (2007/10/02)
Treatment of oxiranes with thiazolidine-2,4-dione gives N-(2-hydroxypropyl)-thiazolidine-2,4-diones which can recyclize to 5-substituted 2-oxazolidones in basic medium.
