19116-94-0Relevant academic research and scientific papers
ACLY INHIBITORS AND USES THEREOF
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Paragraph 00655, (2020/06/01)
The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.
HETEROCYCLIC COMPOUND
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Paragraph 0973, (2019/06/17)
Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
Statistical molecular design, parallel synthesis, and biological evaluation of a library of thrombin inhibitors
Linusson,Gottfries,Olsson,?rnskov,Folestad,Nordén,Wold
, p. 3424 - 3439 (2007/10/03)
A library of thrombin inhibitors has been designed using statistical molecular design. An aromatic scaffold was used, with three varied positions corresponding to three pockets at the active site of thrombin (the S-, P-, and D-pockets). The selection was
