191222-93-2

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 172531-42-9 5-(3-benzoylthiopropyn-1-yl)-2'-deoxyuridine 
• 54-42-2 5-Iodo-2'-deoxyuridine 
• 172531-41-8 5-(3-benzoylthiopropyn-1-yl)-2'-deoxyuridine 3',5'-di-tert-butyldimethylsilyl ether 
• 151867-56-0 5-(3-hydroxypropyn-1-yl)-2'-deoxyuridine 3',5'-di-tert-butyldimethylsilyl ether 
• 148134-86-5 2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine 

Relevant academic research and scientific papers

Very high affinity DNA recognition by bicyclic and cross-linked oligonucleotides

We report the synthesis and DNA incorporation of a novel C-5 thiopropyne-substituted thymidine derivative which can be used to bring about covalent crosslinks between two noncomplementary DNA strands. This modified thymine pairs normally with adenine in d