19124-40-4

Usage

Molecular Structure

A complex chemical compound with a sugar-like structure, derived from glucose.

Acetyl Group

Contains an acetyl group, known for its potential biological activity.

Glucose Derivation

Derived from glucose, a simple sugar.

Unique Structure

The compound has a unique structure that contributes to its value in various applications.

Pharmaceutical Production

Commonly used in the production of pharmaceuticals.

Building Block

Serves as a building block for the synthesis of other complex molecules.

Chemical and Biological Applications

Valuable in various chemical and biological applications, particularly in medicinal chemistry.

Upstream product

• 117177-19-2 2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline 
• 67-63-0 isopropyl alcohol 
• 1040191-33-0 N'-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-p-toluenesulfono-hydrazide 
• 7512-17-6 N-Acetyl-D-glucosamine 

Downstream Products

• 1420235-76-2 isopropyl 2-acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside 
• 1420235-66-0 isopropyl 2-acetamido-2-deoxy-3,6-di-O-benzyl-α-D-glucopyranoside 
• 1420235-74-0 isopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside 

Relevant academic research and scientific papers

Chemo-enzymatic approach to access diastereopure α-substituted GlcNAc derivatives

The formation of diastereopure α-substituted GlcNAc derivatives in a simple and straightforward way is a challenging task. Herein, we report the chemical synthesis of diastereomeric α/β-substituted GlcNAc derivatives under non-anhydrous atmosphere using u

Protecting group free glycosidations using p-toluenesulfonohydrazide donors

(Figure Presented) N-Glycopyranosylsulfonohydrazides are introduced as glycosyl donors for protecting group free synthesis of O-glycosides, glycosyl azides, and oxazolines. Mono- and disaccharides containing a reducing terminal N-acelylglucosamine residue were condensed with p-toluenesulfonylhydrazide to give the desired β-D-pyranose donors. These donors can be activated with NBS and then glycosidated with the desired alcohol or transformed to the oxazoline or glycosyl azide.

Facile approach to 2-acetamido-2-deoxy-β-D-glucopyranosides via a furanosyl oxazoline

(Chemical Equation Presented) A concise and convenient route that may be easily scaled is reported for the preparation of unprotected β-glucopyranosides of N-acetyl-D-glucosamine. Reaction of a wide variety of alcohols with a reactive, readily prepared furanosyl oxazoline under acidic conditions affords the corresponding β-D-glucopyranosides in good to high yields. Primary alcohols gave only β-D-glucopyranosides. A mechanism is proposed for this transformation.