191275-06-6Relevant academic research and scientific papers
A novel synthesis of a key intermediate for penems and carbapenems utilizing lipase-catalyzed kinetic resolution
Seki, Masahiko,Furutani, Toshiyuki,Miyake, Tsutomu,Yamanaka, Takeshi,Ohmizu, Hiroshi
, p. 1241 - 1244 (1996)
Titanium enolate-mediated aldol reaction of N-phthaloyl-β-alanyl-1,3-benzoxazinone 5 with acetaldehyde gave the (±)-syn-aldol (±)-6 in a high yield with high diastereoselectivity. Lipase-catalyzed hydrolysis of the corresponding laurate (±)-7b furnished e
