19132-83-3Relevant academic research and scientific papers
Isolation and synthesis of a novel immunosuppressive 17α- substituted dammarane from the flour of the Palmyrah palm (Borassus flabellifer)
Revesz,Hiestand,La Vecchia,Naef,Naegeli,Oberer,Roth
, p. 1521 - 1526 (2007/10/03)
The novel triterpene 1 with a dammarane skeleton and a hitherto unknown 17α-substitution pattern has been isolated from the Palmyrah palm in low yield and prepared by synthesis in larger quantities. 1 was shown to be an extremely potent immunosuppressant
In vitro conversion of 2,3-oxidosqualene into dammarenediol by Panax ginseng microsomes
Kushiro, Tetsuo,Ohno, Yoshimi,Shibuya, Masaaki,Ebizuka, Yutaka
, p. 292 - 294 (2007/10/03)
(RS)-[3-3H]-2,3-Oxidosqualene (1) was converted into (20S)- dammarenediol (2) and not to (20R)-dammarenediol by a microsomal fraction prepared from the hairy root of Panax ginseng. The enzyme activity was highest at pH 6.0 and was not increased by the addition of any detergents. These properties differed significantly from those of other 2,3-oxidosqualene cyclases reported from higher plants and animals.
