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  • High quality (3R,4S)-1-(4-Fluorophenyl)-3-(3-(4-Fluorophenyl)-3-Oxopropyl)-4-(4-Hydroxyphenyl)Azetidin-2-One supplier in China

    Cas No: 191330-56-0

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  • 1 Kilogram

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  • Simagchem Corporation
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191330-56-0 Usage

Chemical Properties

White to Off-White Solid


Phase-I metabolite of Ezetimibe (E975000).

Check Digit Verification of cas no

The CAS Registry Mumber 191330-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,3,3 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 191330-56:
120 % 10 = 0
So 191330-56-0 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017


1.1 GHS Product identifier

Product name (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one

1.2 Other means of identification

Product number -
Other names 1-(4-fluorophenyl)-3(R)-[3-oxo-3-(4-fluorophenyl)-propyl]-4-(S)-(4-hydroxyphenyl)azetidin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:191330-56-0 SDS

191330-56-0Relevant articles and documents

Ezetimibe intermediate and synthesis method thereof


, (2018/04/02)

The invention provides a new ezetimibe intermediate and a preparation method thereof. The preparation method comprises: (1) converting 4-(4-fluoro-benzoyl)-butyric acid into 4-[2-(4-fluoro-phenyl)-[1,3]dithiolan-2-yl]-butyric acid through a un-separated intermediate compound; and (2) carrying out acylation on chiral oxazolidone by using the 4-[2-(4-fluoro-phenyl)-[1,3]dithiolan-2-yl]-butyric acid to obtain the oxazolidone derivative VI. According to the present invention, the route is simple, cheap and efficient, and the obtained product has advantages of less impurity, high purity, and high yield.

Intermediate compound of ezetimibe


Paragraph 0065; 0074; 0075; 0076; 0086; 0097; 0108; 0119, (2018/04/02)

The invention provides a novel intermediate compound of ezetimibe and a preparation method thereof. The preparation method comprises a step of converting 4-(4-fluoro-benzoyl)-butyric acid into 4-[2-(4-fluoro-phenyl)-[1,3]dithiolan-2-yl]-butyric acid by using an unseparated intermediate compound. The method provided by the invention is simple in route, low in price and high in efficiency; and in order to better protect functional groups, the method employs the selectively removable protective group, so the method has the advantages of few impurities, high product purity and high product yield.

Preparation method of ezetimibe and key intermediates thereof of lipid-lowering drugs


, (2017/09/13)

The invention relates to a preparation method of ezetimibe and key intermediates thereof of lipid-lowering drugs. The preparation method is applicable to industrial production.

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