191337-28-7Relevant academic research and scientific papers
Derivatized oxopiperazine rings from amino acids
Bhatt, Ulhas,Mohamed, Nazim,Just, George,Roberts, Edward
, p. 3679 - 3682 (1997)
Two routes for the synthesis of derivatized oxopiperazines, which may act as constrained peptide mimics, are reported. The syntheses employ reductive amination and sulfonamide approaches for generating N-allylic amino acid ester derivatives and utilizing them for assembling the ring systems. An aspartame analog was prepared using this methodology.
