191408-13-6

Basic information

• Product Name: (2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl-benzenesulfonyl)-1,7-diaza-cyclotridecane-2,11-dicarboxylic acid 11-(benzyloxy-amide) 2-methylamide
• CAS NO: 191408-13-6
• Molecular Weight: 642.86
• Mol File: 191408-13-6.mol

Chemical Properties

• CAS DataBase Reference: (2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl-benzenesulfonyl)-1,7-diaza-cyclotridecane-2,11-dicarboxylic acid 11-(benzyloxy-amide) 2-methylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl-benzenesulfonyl)-1,7-diaza-cyclotridecane-2,11-dicarboxylic acid 11-(benzyloxy-amide) 2-methylamide(191408-13-6)
• EPA Substance Registry System: (2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl-benzenesulfonyl)-1,7-diaza-cyclotridecane-2,11-dicarboxylic acid 11-(benzyloxy-amide) 2-methylamide(191408-13-6)

Safety Data

• Hazardous Substances Data: 191408-13-6(Hazardous Substances Data)

Upstream product

• 622-33-3 N-benzyloxyamine 
• 191406-75-4 4-benzyl 1-tert-butyl (2S,3R)-2-(3-hydroxypropyl)-3-isobutylbutanedioate 
• 191406-74-3 (2R,3S)-3-(tert-butoxycarbonyl)-2-isobutylhex-5-enoic acid benzyl ester 
• 191409-63-9 (2S,3R)-2-(3-Hydroxy-propyl)-5-methyl-3-[(S)-1-methylcarbamoyl-5-(2,4,6-trimethyl-benzenesulfonylamino)-pentylcarbamoyl]-hexanoic acid tert-butyl ester 
• 191408-12-5 tert-butyl (6S,9R,10S)-9-isobutyl-6-[(methylamino)carbonyl]-8-oxo-1-(mesitylsulfonyl)-1,7-diazacyclotridecane-10-carboxylate 
• 229318-21-2 (2R,3S)-3-(tert-butoxycarbonyl)-6-hydroxy-2-isobutylhexanoic acid 

Relevant articles and documents

Macrocyclic hydroxamate inhibitors of matrix metalloproteinases and TNF- α production

Several macrocyclic, hydroxamate derivatives were synthesized and evaluated as inhibitors of matrix metalloproteinases (MMPs) and turnout necrosis factor-α (TNF-α) production. These macrocycles are anti-succinate based inhibitors linked from P1 to P2'. A