19141-74-3

Basic information

• Product Name: (3-chloropropyl)oxirane
• Synonyms: (3-chloropropyl)oxirane;5-CHLORO-1,2-EPOXYPENTANE;Einecs 242-835-5
• CAS NO: 19141-74-3
• Molecular Formula: C₅H₉ClO
• Molecular Weight: 120.57736
• EINECS: 242-835-5
• Mol File: 19141-74-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 155.2°Cat760mmHg
• Flash Point: 47.1°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 3.95mmHg at 25°C
• Refractive Index: 1.452
• CAS DataBase Reference: (3-chloropropyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (3-chloropropyl)oxirane(19141-74-3)
• EPA Substance Registry System: (3-chloropropyl)oxirane(19141-74-3)

Safety Data

• Hazardous Substances Data: 19141-74-3(Hazardous Substances Data)

Usage

General Description

(3-chloropropyl)oxirane, also known as glycidyl 3-chloropropyl ether, is a chemical compound with the molecular formula C6H11ClO. It is a colorless, flammable liquid that is primarily used as a reactive diluent or a crosslinking agent in epoxy resins. It is commonly used in the production of plastics, adhesives, and coatings. (3-chloropropyl)oxirane is known to be a skin and eye irritant, and prolonged exposure may cause respiratory and skin sensitization. It is important to handle this chemical with caution and follow proper safety protocols when working with it.

InChI:InChI=1/C5H9ClO/c6-3-1-2-5-4-7-5/h5H,1-4H2

Upstream product

• 89280-57-9 1,5?dichloro?2?pentanol 
• 821-09-0 n-Pent-4-enyl alcohol 
• 928-50-7 5-chloropent-1-ene 

Downstream Products

• 85275-45-2 N-tert-butoxycarbonyl-3-piperidinol 
• 6859-99-0 3-hydroxypiperazine 
• 94157-97-8 1?amino?5?chloro?2?pentanol 
• 20074-80-0 5-chloro-pentanal 
• 63791-08-2 1,1,1-triphenyl-hexahydro-cyclopenta[c][1,2]oxaphosphole 
• 63791-00-4 7,7,7-triphenyl-6-oxa-7λ⁵-phospha-bicyclo[3.2.1]octane 

Relevant articles and documents

Preparation method of (S)-N-BOC-3-hydroxypiperidine

The invention provides a preparation method of (S)-N-BOC-3-hydroxypiperidine. The preparation method comprises the following steps: carrying out a reaction on (S)-epichlorohydrin with a 2-chloroethylmagnesium bromide Grignard reagent to obtain (S)-1,5-dichloro-2-pentanol, carrying out an intramolecular cyclization reaction in the presence of an alkaline substance to generate (S)-5-chloro-1,2-epoxypentane, carrying out a reaction on the (S)-5-chloro-1,2-epoxypentane with an ammonia solution to generate (S)-1-amino-5-chloro-2-pentanol, then carrying out an intramolecular cyclization reaction onthe (S)-1-amino-5-chloro-2-pentanol to obtain (S)-3-hydroxypiperidine, and finally carrying out a reaction with BOC anhydride to obtain the product (S)-N-BOC-3-hydroxypiperidine. The preparation method disclosed by the invention has the advantages of short synthesis route, few side reactions and high yield; the product has good quality and is convenient for purification. The raw materials are easily available and has low price; the reaction conditions are mild; and safety is high. The preparation method is environmentally friendly, is simple and practice, and is suitable for industrial batchproduction.