191484-60-3

Upstream product

• 104-20-1 4-(4-methoxyphenyl)-2-butanone 
• 943-88-4 4-(p-methoxyphenyl)-3-butene-2-one 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1078-28-0 6-methoxyquinaldine 
• 161644-20-8 2-methyl-1-azaspiro[4.5]deca-1,6,9-trien-8-one 
• 646039-18-1 6-methoxy-2-methyl-3,4-dihydroquinoline 

Relevant academic research and scientific papers

Synthesis of Quinolines and 2H-Dihydropyrroles by Nucleophilic Substitution at the Nitrogen Atom of Oxime Derivatives

Isomerization of oxime derivatives was researched in detail to find out the methods for the syn-anti isomerization of O-substituted oximes. Based on these findings were developed simple methods for the preparation of aza-heterocycles from both stereoisomers of oximes. Quinolines were synthesized from β-aryl ketone oximes by treatment with trifluoroacetic anhydride and 4-chloranil. γ,δ-Unsaturated O-methoxyacetyloximes were transformed to 2H-dihydropyrroles by reaction with methoxy-acetic acid.