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19156-47-9

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19156-47-9 Usage

General Description

Ethyl 5-(2-acetoxyethyl)-4-Methylthiophene-3-carboxylate is a chemical compound that belongs to the class of esters. It is a derivative of thiophene, which is a five-membered aromatic ring with one sulfur atom. The compound contains an ethyl group, a 2-acetoxyethyl group, and a 4-methylthiophene-3-carboxylate group. It is commonly used in the synthesis of pharmaceuticals and agrochemicals, where it serves as a building block for creating more complex molecules. ethyl 5-(2-acetoxyethyl)-4-Methylthiophene-3-carboxylate may have potential applications in the fields of medicine and agriculture due to its chemical properties and structure.

Check Digit Verification of cas no

The CAS Registry Mumber 19156-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,5 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19156-47:
(7*1)+(6*9)+(5*1)+(4*5)+(3*6)+(2*4)+(1*7)=119
119 % 10 = 9
So 19156-47-9 is a valid CAS Registry Number.

19156-47-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 5-(2-acetyloxyethyl)-4-methylthiophene-3-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19156-47-9 SDS

19156-47-9Downstream Products

19156-47-9Relevant articles and documents

Differences in the efficiency of 3-deazathiamine and oxythiamine pyrophosphates as inhibitors of pyruvate dehydrogenase complex and growth of HeLa cells in?vitro

Grabowska, Ewa,Czerniecka, Magdalena,Czy?ewska, Urszula,Zambrzycka, Aneta,?otowski, Zenon,Tylicki, Adam

, p. 122 - 129 (2020/11/16)

Oxythiamine (OT) and 3-deazathiamine (DAT) are the antimetabolites of thiamine. The aim of study was to compare the effects of OT and DAT pyrophosphates (-PP) on the kinetics of mammalian pyruvate dehydrogenase complex (PDHC) and the in?vitro culture of HeLa cells. The kinetic study showed that 3-deazathiamine pyrophosphate (DATPP) was a much stronger competitive inhibitor (Ki = 0.0026 μM) of PDHC than OTPP (Ki = 0.025 μM). Both Ki values were much lower versus K m for thiamine pyrophosphate (0.06 μM). However, DATPP added to the culture medium for the HeLa cells culture did not hamper the rate of cell growth and showed not significant impact on the viability of the cells, whereas OTPP and OT showed a significant cytostatic effect. The differences between the thiamine antivitamins in their effect on cell growth in?vitro may be due to differences in physicochemical properties and difficulty in DAT transport across the cell membrane.

Synthesis of 3-deazathiamine

Hawksley, Daniel,Griffin, David A.,Leeper, Finian J.

, p. 144 - 148 (2007/10/03)

An efficient ten-step synthesis of deazathiamine is described. The synthesis starts from commercially available α-acetyl-γ-butyrolactone and proceeds via deamination of the key aminothiophene 6. The Gewald synthesis of thiophenes is shown to give a mixture of isomeric products with the unsymmetric ketone used here and so a modified procedure giving a single isomer is developed.

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