19156-54-8

Basic information

• Product Name: 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID
• Synonyms: 4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid(SALTDATA: FREE);4,5,6,7-Tetrahydro-ben[B]thiophene-3-carboxylic acid;2-broMo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid;4,5,6,7-Tetrahydrobenzothiophene-3-carboxylic acid
• CAS NO: 19156-54-8
• Molecular Formula: C₉H₁₀O₂S
• Molecular Weight: 182.24
• EINECS: 624-553-8
• Mol File: 19156-54-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 179-184°C
• Boiling Point: 350.5°Cat760mmHg
• Flash Point: 165.8°C
• Appearance: /
• Density: 1.317g/cm³
• Vapor Pressure: 1.63E-05mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID(19156-54-8)
• EPA Substance Registry System: 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID(19156-54-8)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 19156-54-8(Hazardous Substances Data)

Usage

General Description

4,5,6,7-Tetrahydro-benzo[b]thiophene-3-carboxylic acid is a chemical compound that contains a benzo[b]thiophene ring system. It is a carboxylic acid derivative, which means it contains a carboxyl group (-COOH) attached to the benzothiophene ring. 4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID is a heterocyclic compound, containing both carbon and sulfur atoms in its ring structure. It may have potential applications in organic synthesis, pharmaceuticals, or agrochemicals due to its unique structure and properties. Further research and experimentation may be needed to fully understand and utilize the potential of 4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid in various industries.

InChI:InChI=1/C9H10O2S/c10-9(11)7-5-12-8-4-2-1-3-6(7)8/h5H,1-4H2,(H,10,11)

Upstream product

• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 14559-12-7 ethyl 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 

Downstream Products

• 398137-02-5 N-[3-cyano-4-(4-hydroxypiperidin-1-yl)phenyl]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 913526-84-8 2-(4,5,6,7-tetrahydrobenzo[b]thiophene-3-yl)ethanamine 
• 314251-04-2 N-[5-(4-fluorobenzyl)-1,3-thiazol-2-yl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide 

Relevant articles and documents

Ethyl 2-Aminothiophene-3-Carboxylates in the Synthesis of Isomeric Thienopyridines

A convenient method for the synthesis of thieno[3,2-c]pyridinones was developed. A number of thiophene derivatives was prepared, and the possibility of using thiophene desamino derivatives for the design of potentially biologically active molecules was demonstrated.

Fused bicyclic amide compounds and medicinal use thereof

The present invention provides a compound represented by the formula (I) wherein ring A is benzene, cyclohexane, pyridine, piperidine or a derivative thereof, imidazole or a derivative thereof and the like, ring B is benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene and the like, R1, R2 and R3 are each hydrogen, alkyl, halogen, hydroxyl group, alkoxy and the like, W is hydrogen, alkyl or hydroxycarbonylalkyl, X is halogen, cyano, nitro and the like, X′ is hydrogen, halogen and the like, and Y is alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl and the like, a salt thereof, and a pharmaceutical agent containing the compound. The compound of the present invention shows a superior inhibitory effect on the proliferation of activated lymphocyte and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.