191660-23-8

Upstream product

• 191660-32-9 Toluene-4-sulfonic acid (2R,4R)-5-(tert-butyl-diphenyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-pentyl ester 
• 191660-28-3 (5R,7R)-5,7-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-[1,3,2]dioxathiocane 2,2-dioxide 
• 191660-30-7 (2S,4S)-2,4-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-pentane-1,5-diol 
• 191660-31-8 (2S,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-pentan-1-ol 
• 2973-86-6 lithium thiophenoxide 

Downstream Products

• 193278-19-2 (2R,4R)-2-Benzenesulfinylmethyl-4-methyl-pentane-1,5-diol 
• 193278-14-7 (2R,4S)-5-Benzenesulfonyl-4-chloromethyl-2-methyl-pentan-1-ol 
• 193278-31-8 ((2R,4R)-4-Methyl-5-triethylsilanyloxy-2-triethylsilanyloxymethyl-pentane-1-sulfinyl)-benzene 

Relevant academic research and scientific papers

The sily-durst chlorination of hydroxy sulfoxides

Treatment by sulfuryl chloride of the bis-O-TES derivative of a γ,ε-bis-hydroxy phenylsulfoxide resulted in the selective formation of the corresponding γ-chloro-ε-hydroxy phenylsulfone.

Toward a total synthesis of an aglycone of spiramycine; two complementary accesses to a C-5/C-9 fragment

Both homochiral acetates 4d and 5f, which were obtained by lipase-catalysed acetylation of either the tetraol 4a or the diol 5e, respectively, have been converted stereoconvergently into a C-5/C-9 fragment of the title antibiotic.