Welcome to LookChem.com Sign In|Join Free

CAS

  • or

191668-32-3

Post Buying Request

191668-32-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

191668-32-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 191668-32-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,6,6 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 191668-32:
(8*1)+(7*9)+(6*1)+(5*6)+(4*6)+(3*8)+(2*3)+(1*2)=163
163 % 10 = 3
So 191668-32-3 is a valid CAS Registry Number.

191668-32-3Relevant articles and documents

N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-yl methyl)methylamines related to naftifine. Synthesis and antifungal activity

Di Santo, Roberto,Costi, Roberta,Artico, Marino,Massa, Silvio,Musiu, Chiara,Milia, Carlo,Putzolu, Monica,La Colla, Paolo

, p. 98 - 108 (2007/10/03)

Various pyrrole analogues of the antifungal drug naftifine were prepared starting from cinnamates via the tosylmethylisocyanide (TosMIC) reaction. After alkylation and hydrolysis, the intermediate arylpyrrole esters afforded 1-alkyl-4-aryl-1H-pyrrole-3-carboxylic acids, which were condensed with N-(1-naphthylmethyl)methylamine in the presence of EDCI and triethylamine. The related amides were then reduced with lithium aluminum hydride to the required N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-ylmethyl)methylamines. The new compounds were evaluated for antifungal activity in comparison with naftifine and other imidazole drugs used in the clinic. Derivative 7c was active against Candida parapsilosis and compound 51 against Candida albicans. Weak activity against dermatophytes was shown by a number of derivatives. Moreover, compounds 4g, 4j, 4k and 4p were found active against Staphylococcus aureus with potencies comparable to that of streptomycin.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 191668-32-3