191725-56-1

Basic information

• Product Name: Benzene, 1-chloro-4-(2-methoxy-1-methylethenyl)-
• CAS NO: 191725-56-1
• Molecular Formula: C10H11ClO
• Molecular Weight: 182.65
• Mol File: 191725-56-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-(2-methoxy-1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-(2-methoxy-1-methylethenyl)-(191725-56-1)
• EPA Substance Registry System: Benzene, 1-chloro-4-(2-methoxy-1-methylethenyl)-(191725-56-1)

Safety Data

• Hazardous Substances Data: 191725-56-1(Hazardous Substances Data)

Upstream product

• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 99-91-2 para-chloroacetophenone 

Downstream Products

• 75854-92-1 (p-chlorophenyl)-4 methyl-4 cyclohexene-2 one-1 
• 126866-18-0 1-phenyl-2-(4-chlorophenyl)-propan-1-one 
• 102877-35-0 2-(4-chlorophenyl)-propane-1,2-diol 

Relevant articles and documents

Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.

Nickel-Catalyzed Desymmetric Hydrogenation of Cyclohexadienones: An Efficient Approach to All-Carbon Quaternary Stereocenters

Nickel-catalyzed desymmetric hydrogenation has been achieved. With the Ni(OTf)2/(S,S)-Ph-BPE system, a series of ?,?-disubstituted cyclohexadienones were transformed to the corresponding cyclohexenones with a chiral all-carbon quaternary center at the γposition in high yields (92-98%) and excellent enantioselectivities (92%-99% ee). This catalytic system can also tolerate the desymmetric reaction of spirocarbocyclic cyclohexadienones to produce the corresponding cyclohexenones bearing a chiral spiro quaternary carbon with high yields (94%-98%) and ee values (96%-99% ee). Furthermore, this methodology provides an efficient and concise synthetic route to the intermediate of natural products cannabispirenones A and B.

Rhodium-catalyzed asymmetric hydrogenation of β-branched enamides for the synthesis of β-stereogenic amines

Using a rhodium complex of a bisphosphine ligand (R)-SDP, β-branched simple enamides with a (Z)-configuration were hydrogenated to β-stereogenic amines in quantitative yields and with excellent enantioselectivities (88-96% ee).