191729-21-2 Usage
General Description
2-Chloro-4-(phenylthio)pyrimidine is a chemical compound with the molecular formula C10H7ClN2S. It is a pyrimidine derivative that contains a chlorine atom and a phenylthio group (C6H5S) attached to the pyrimidine ring. 2-CHLORO-4-(PHENYLTHIO)PYRIMIDINE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, it can also be used as a building block for the preparation of various other functionalized pyrimidine derivatives. Its versatile reactivity and potential as a key building block in organic synthesis make it a valuable compound in the field of medicinal and agricultural chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 191729-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,7,2 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 191729-21:
(8*1)+(7*9)+(6*1)+(5*7)+(4*2)+(3*9)+(2*2)+(1*1)=152
152 % 10 = 2
So 191729-21-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H7ClN2S/c11-10-12-7-6-9(13-10)14-8-4-2-1-3-5-8/h1-7H
191729-21-2Relevant articles and documents
HFIP Promoted Low-Temperature SNAr of Chloroheteroarenes Using Thiols and Amines
Bhujabal, Yuvraj B.,Vadagaonkar, Kamlesh S.,Gholap, Aniket,Sanghvi, Yogesh S.,Dandela, Rambabu,Kapdi, Anant R.
, p. 15343 - 15354 (2019/12/04)
A highly efficient and an unprecedented hexafluoro-2-propanol, promoting low-temperature aromatic nucleophilic substitutions of chloroheteroarenes, has been performed using thiols and (secondary) amines under base-free and metal-free conditions. The developed protocol also provides excellent regio-control for the selective functionalization of dichloroheteroarenes, while the utility of the protocol was demonstrated by the modification of a commercially available drug ceritinib.
SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS
-
, (2008/06/13)
-
