191731-19-8Relevant academic research and scientific papers
A simple, stereoselective synthesis of ketomethylene dipeptide isosteres
Hoffman, Robert V.,Tao, Junhua
, p. 7119 - 7126 (1997)
An exceedingly simple, general, and stereoselective method for the preparation of ketomethylene dipeptide isosteres (5-(carbobenzyloxyamino)-2-alkyl-γ-ketoesers) from Cbz-protected amino acids and scalemic-2-triflyloxy esters has been developed. The method is short (three steps), efficient, and highly diastereoselective and enantioselective.
